Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:### Lac Regulation Circuit Diagram
#### Instruction:
Fill in each box within the diagram of the lac regulation circuit below with the **LETTER (A-L)** that corresponds to the correct gene or protein chosen from the following list. Each letter should be used only once.
#### List of Genes and Proteins:
- A) cAMP
- B) lacI protein
- C) CAP gene
- D) Glucose
- E) Lactose
- F) β-galactosidase
- G) ATP
- H) Galactose
- I) CAP protein
- J) Adenylyl Cyclase
- K) Lac operon
- L) Lac I
#### Diagram Explanation:
The diagram represents the lac operon regulatory circuit and contains the following annotations:
1. **Box D**: Glucose
2. **Box J**: Adenylyl Cyclase
3. **Box G**: ATP
4. **Box A**: cAMP
5. **Box I**: CAP Protein
6. **Box E**: Lactose
7. **Box B**: lacI Protein
To summarize, the diagram reflects how the presence or absence of glucose affects the adenylyl cyclase activity, the conversion of ATP to cAMP, the subsequent activation of CAP protein, and the role of lactose in the system. This ultimately influences the expression of lac operon genes – lacZ, lacY, and lacA via the regulation by the lacI protein.
Here is the completed layout with the correct assignments of genes and proteins according to the specific letters (A-L):
- Glucose (D) inhibits Adenylyl Cyclase (J).
- ATP (G) is converted by Adenylyl Cyclase (J) into cAMP (A).
- cAMP (A) interacts with CAP Protein (I).
- Lactose (E) interacts with lacI Protein (B), affecting the lac operon system, involving genes lacZ, lacY, and lacA.
The arrows indicate the direction of interactions or regulatory control in the system.
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