Concerning the use of pyruvate when ratio of NADH/NAD+ is low, what is the fate of the carbon labeled in pyruvate when metabolized under these conditions? a) Production of glucose b) Oxidation to CO2 via the TCA cycle c) Conversion to pyruvate to generate oxaloacetate to move electrons to the cytosol via the malate shuttle d) Pyruvate is never metabolized by the cell, instead pyruvate is converted to lactate and solely exported for the Cori cycle and dependent on the liver to recycle the carbon skeleton
Concerning the use of pyruvate when ratio of NADH/NAD+ is low, what is the fate of the carbon labeled in pyruvate when metabolized under these conditions? a) Production of glucose b) Oxidation to CO2 via the TCA cycle c) Conversion to pyruvate to generate oxaloacetate to move electrons to the cytosol via the malate shuttle d) Pyruvate is never metabolized by the cell, instead pyruvate is converted to lactate and solely exported for the Cori cycle and dependent on the liver to recycle the carbon skeleton
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Concerning the use of pyruvate when ratio of NADH/NAD+ is low, what is the fate of the carbon labeled in pyruvate when metabolized under these conditions?
a) Production of glucose
b) Oxidation to CO2 via the TCA cycle
c) Conversion to pyruvate to generate oxaloacetate to move electrons to the cytosol via the malate shuttle
d) Pyruvate is never metabolized by the cell, instead pyruvate is converted to lactate and solely exported for the Cori cycle and dependent on the liver to recycle the carbon skeleton
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