Melanoma, 45| Colon cancer, 40 Sarcoma, 45 Breast cancer, 32 Lung cancer, 53 Stomach cancer, 50 Brain cancer, 18 Osteosarcoma, 3 Leukemia, 19 Rhabdomyosarcoma, 14 Answer the following subparts :- A. What do you notice in this pedigree as compared to Rb or BRCA1/2? B. Why do you think that so many cancer types are associated with inherited defects in p53? Please need detailed answer I want to learn please please I will upvote god promisel

Q: The BCRA-1 allele is associated with very high risk of breast and ovarian cancers. Is this allele…

A: The mutation accumulation (MA) theory describes that if harmful or deleterious mutations are…

Q: What is the progressive developmental model of public health that Livingston is talking about?  How…

A: Note:- sorry, as per our company's honor code, using external references is not allowed. Thank you!…

Q: Suppose that a female with the mutation (i.e., a heterozygous female) mates with a healthy male (the…

A: Alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: 1 at birth 1 2 This pedigree illustrates the occurrence of neurofibromatosis in a small human family…

A: A pedigree is a chart that delineates the hereditary ties and patterns of inheritance between…

Q: Jonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis, caused by inheriting…

A: Given: Jonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis,caused by…

Q: Please answer fast What is "variable penetrance"? Explain why autosomal dominant disease penetrance…

A: Autosomal disease The disease which is caused by the autosomal set of chromosome except the X and Y…

Q: Imagine that individual V-8 marries a female cousin who is a carrier of the 5αRD mutation. What is…

A: A person must carry two copies of the defective gene (one from every parent) in order to have…

Q: Three people are diagnosed with different types of cancer. One is a lifelong smoker and has lung…

A: Chronic inflammation increases the relative risk for many type of cancers. Toxins released from…

Q: to understand the disease and how to deal with it. The process involves studying family history,…

A: The idea that disorders are inherited has been prevailing in the human society since long. This was…

Q: Inherited cancers are due to mutations in ________ cells. They are/are not passed on to offspring.…

A: Cancer is a disease where some cells of the body divide uncontrollably and they can also infiltrate…

Q: Problem 1) Tay-Sachs disease is caused by loss of function mutation in a gene on chromosome 15 that…

A: Tay Sach disease is an autosomal recessive inheritance.  Let T gene encodes normal phenotype and it…

Q: QUESTION 1 An individual with hypertrichosis has hair growing in areas of the body where hair does…

A: Hypertrichosis, also known as "werewolf syndrome," is a medical condition characterized by excessive…

Q: Standard 2b A male individual who is XYSRY has the following genotype for the AMH gene on chromosome…

A: Humans have 23 pairs of chromosomes of which 22 pairs are autosomal and the 23rd pair is…

Q: Fragile X syndrome What are the symptoms or characteristics of this disorder or trait?  What is…

A: Fragile X syndrome   Fragile X syndrome (FXS) is a disorder which causes mainly mental and…

Q: Mrs. Ortez has type III breast cancer and is now concluding the trial portion of a certain research…

A: Stage III breast cancer is a stage where the cancer has spread beyonf the tumor region and might…

Q: Explain how familial retinoblastoma is inherited at the: a. Čellular level Vs. b. The pedigree level…

A: The cells of the retina of the eye are where retinal blastoma begins. A mass of cancer cells known…

Q: Parent A CFTRwt CFTRG511D CFTRwt CFTRwt CFTRwt CFTR GST G511D Healthy Healthy CFTRwt CFTRAF508…

A: Cystic fibrosis occurs when there is a mutation in CFTR gene that forms CFTR ( cystic fibrosis…

Q: Consider the same hypothesis: Bone cells treated with vitamin D generate an increased amount of bone…

A: 1 This hypothesis is an alternative directional hypothesis.It states that bone cells treated with…

Q: Why is the Philadelphia chromosome important to understanding & treating some cancers, especially…

A: Philadelphia chromosome is only present in the blood cells that are affected because of the damaged…

Q: Sickle cell disease— what is the background of this disorder: include the name of the disorder, any…

A: Sickle cell disease is a genetic condition characterized by abnormal hemoglobin in red blood cells.

Q: Question 3: A woman suffers from albinism and is also a carrier for haemophilia. Draw a well-…

A:

Q: a often survive until adulthood and produce children, what is their risk of developing other types…

A: Retinoblastoma is  an uncommon type of eye cancer that occurs in the young children and in this type…

Q: A genetic autoimmune disease is caused by a single recessive allele a that is located on the…

A: In this genetic scenario, a rare autoimmune disease is caused by a single recessive allele, denoted…

Q: Please help True or false, if false rewrite the statement in a way that makes it true. a) A cell…

A: A cell can be defined as the basic structural, functional, and biological unit of all known living…

Q: In "Your Genes, Your Choices," Priya is concerned about Huntington's disease, an autosomal dominant…

A: This is a disease that is autosomal dominant. It is an inherited neurodegenerative disease that…

Q: 5 1 point What is the most likely mode of inheritance of the disease depicted in the following…

A: Pedigree is historical record of of ancestry, showing lineage. It is very useful in finding out the…

Q: man has a child with a woman who does not carry the dominant disease allele, what is the probability…

A:

Q: Many genetic counselors will not provide presymptomatic genetic testing for Huntington disease to…

A: The genes are the hereditary unit of the organism that is passed on by the parents to the offspring.…

Q: he propensity to develop retinal cancer can run in pedigrees of certain families. You have learned…

A: Tumor suppressor genes are important cancer prevention genes since a partial or total inactivation…

Q: What is the phenotype of the genetic disorder?   2. How does it express itself? 3. Does it cause…

A: according to bartleby guidelines, I can answer only first three, kindly repost the remaining…

Q: parents Imagine two heterozygous for cystic fibrosis come to ask you about the probability of their…

A: Introduction:- A Pedigree is a family tree, consisting of symbols and lines that shows the pattern…

Q: Neurofibromatosis type 1 (NF1) is an inherited is an inheritent dominant disorder. The phenotype…

A: Neurofibromatosis (NF) is a genetic neurological disorder that can affect the brain, spinal cord,…

Q: Part A What is the probability that the first son of a woman whose brother has Lesch-Nyhan syndrome…

A: Lesch Nyhan syndrome is X linked recessive disorder. Normal = XX, XXn, XY Affected = XnXn, XnY

Q: Cystic fibrosis in humans is caused by mutations in a single gene and is inherited as an autosomal…

A: Cystic Fibrosis (CF) is an inherited disease that is caused by mutations in gene which is passed…

Q: The pedigree below shows inheritance of a particular autosomal trait across three generations. Males…

A: Pedigree is a family tree that is made up of symbols and line. Pedigree represents person’s family…

Q: 1-Gigantism is being traced in a family through a pedigree. Its mode of inheritance is thought to be…

A: In autosomal recessive inheritance pattern both males and females are equally affected. The mutation…

Q: DNA sequencing of your own two β-globin genes (one from each of your two Chromosome 11s) reveals a…

A: I should be worried since presence of an abnormal beta globin chains may be an early indicator of…

Q: Please help me with the following question: Von Willebrand disease is an inherited bleeding…

A: Von Willebrand disease is a chronic bleeding disorder that causes your blood to clot improperly.…

Q: 3. Red-green color blindness is caused by an X-linked recessive allele. Suppose a color-blind man…

A: Suppose, the color blind allele is Xc (recessive) and the normal wild type allele is X. Now, in the…

Q: 1. You have 3 turtles, each with a mutation that causes them to have a strange polka dotted pattern…

A: DNA (deoxyribonucleic acid) accounts for the characters present in an organism and its shape and…

Q: mutation in the TCOF1 gene causes up to 93% of Treacher Collins syndrome cases. This gene, which is…

A: Treacher Collins syndrome is caused due to either a mutation on the TCOF1 gene present on chromosome…

Q: Bloom Syndrome Bloom syndrome is a rare genetic disorder. It is characterized by short stature and…

A: The copying of DNA to make more DNA is known as DNA replication, Watson and Crick proposed that each…