Sickle cell disease— what is the background of this disorder: include the name of the disorder, any alternate names used, provide a description of the disorder, and the typical age of onset. What is the Type of genetic disorder: explain if and how this disorder is inherited. Explain the genetic causes of the disorder. Is it inherited? Is the disorder a dominant or recessive trait? Which chromosome is affected in this disorder? Is a gene mutated? If so, name the gene that is affected? How is gene expression impacted (is it a particular type of mutation, a case of a misshapen protein, etc.?)

Q: What is the definition of Driver Mutations & Passenger Mutations? Also describe why each are…

A: A mutation is a change in an organism's DNA sequence. Mutations can occur as a result of errors in…

Q: In a few sentences, describe how p53 guards the genome. Include at least two specific ways that p53…

A: The TP53 ( Tumor protein 53) also known as P53. This gene codes for cell cycle regulatory proteins…

Q: Describe three types of genetic changes that commonly convert aproto-oncogene to an oncogene.…

A: The genetic alteration results in the advantage in growth of the cell. The 3 genetic change…

Q: The development of colon cancer is particularly well- studied, and often has a predictable order of…

A: Colorectal cancer (CRC) is the 1/3 most frequent cancer in men and the 2nd most frequent cancer in…

Q: In cancer like disease, what kind of mutations are more focussed? Single Nucleotide Polymorphism or…

A: Introduction  Cancer is well known disease now a day. In US, 1 in 2 women and 1 in 3 men develops…

Q: c. Explain how this phenomenon relates to hybrid dysgenesis, described in Problem 29 of Chapter 13.

A: The P element in the Drosophila is the transposon genes. The transposons or transposable elements…

Q: How does the structure of a Barr body affect gene expression? B. Color-blindness is an X-linked…

A: Color blindness is characterized by an inability to differentiate between different shades of…

Q: b. How is the DNA information used to make proteins for ongoing cellular processes and cellular…

A: Introduction DNA is the molecular structure that is composed of a pair of polynucleotide chains and…

Q: Discuss why X-linked disorders are more common thanY-linked disorders.

A: Inheritance or heredity is passing-on one trait from the parents to the progeny by either asexual or…

Q: Fragile X syndrome What are the symptoms or characteristics of this disorder or trait?  What is…

A: Fragile X syndrome   Fragile X syndrome (FXS) is a disorder which causes mainly mental and…

Q: gene is usually zed to the clotting when a blood emophilia A, occurs the gene will express women.…

A: Hemophilia is a rare condition in which the blood does not clot properly due to a lack of…

Q: 8.7 Red-Green Color Blindness Problem: Red-Green color blindness is due to the inheritance of an…

A: Let Xc be the defected allele In X-linked recessive disorders, the male can never be a carrier…

Q: Explain what a mutation is and how it can cause a genetic disease.

A: Every cell after a certain growth and development it divides. Cell division occurs follwed by…

Q: In Cystic Fibrosis: How is the gene/chromosome affected? How is the cell, tissue, and body systems…

A: Cystic fibrosis is an innate sickness that influences the lungs and stomach related framework. The…

Q: B C D E E- . What are p53 genotypes of the following tissues (represent the wild-type allele with +…

A: By the help of gel electrophoresis one can determine the genotype. There could be three types of…

Q: Describe the primary causes, types, and outcomes of mutations.Give an example of a mutation that is…

A: Although the genetic information carried by an organism is replicated with the utmost fidelity,…

Q: What is the relationship between beta-amyloid and the protein APP? How does the APP protein differ…

A: It is a progressive neurological disorder that causes the brain to shrink and brain cells to die.

Q: Bloom Syndrome Bloom syndrome is a rare genetic disorder. It is characterized by a short stature…

A: Bloom syndrome is effected by mutations in the BLM gene. Individuals with Bloom syndrome may evolve…

Q: the

A: Cells maintain a steady state called homeostasis. When the cell is in homeostasis, the intracellular…

Q: Describe the underlying causes of epigenetic changes associated with cancer.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Fragile X syndrome why is interesting Fragile X syndrome  What are the symptoms or characteristics…

A: As per our policy, We are answering only question first 5. For the rest of the questions please…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.