Many drugs decompose in blood by a first-order process.(a) Two tablets of aspirin supply 0.60 g of the active compound.After 30 min, this compound reaches a maximum concentra-tion of 2 mg/100 mL of blood. If the half-life for its break-down is 90 min, what is its concentration (in mg/100 mL) 2.5 h after it reaches its maximum concentration?(b) For the decomposition of an antibiotic in a person with a nor-mal temperature (98.6°F), k=3.110⁻⁵s⁻¹; for a person witha fever at 101.9°F, k=3.910⁻⁵s⁻¹. If the person with thefever must take another pill when of the first pill has decom-posed, how many hours should she wait to take a second pill? A third pill? (Assume the pill is effective immediately.)(c) Calculate Eₐ for decomposition of the antibiotic in part (b)
Many drugs decompose in blood by a first-order process.(a) Two tablets of aspirin supply 0.60 g of the active compound.After 30 min, this compound reaches a maximum concentra-tion of 2 mg/100 mL of blood. If the half-life for its break-down is 90 min, what is its concentration (in mg/100 mL) 2.5 h after it reaches its maximum concentration?(b) For the decomposition of an antibiotic in a person with a nor-mal temperature (98.6°F), k=3.110⁻⁵s⁻¹; for a person witha fever at 101.9°F, k=3.910⁻⁵s⁻¹. If the person with thefever must take another pill when of the first pill has decom-posed, how many hours should she wait to take a second pill? A third pill? (Assume the pill is effective immediately.)(c) Calculate Eₐ for decomposition of the antibiotic in part (b)
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Many drugs decompose in blood by a first-order process.(a) Two tablets of aspirin supply 0.60 g of the active compound.After 30 min, this compound reaches a maximum concentra-tion of 2 mg/100 mL of blood. If the half-life for its break-down is 90 min, what is its concentration (in mg/100 mL) 2.5 h after it reaches its maximum concentration?(b) For the decomposition of an antibiotic in a person with a nor-mal temperature (98.6°F), k=3.110⁻⁵s⁻¹; for a person witha fever at 101.9°F, k=3.910⁻⁵s⁻¹. If the person with thefever must take another pill when of the first pill has decom-posed, how many hours should she wait to take a second pill? A third pill? (Assume the pill is effective immediately.)(c) Calculate Eₐ for decomposition of the antibiotic in part (b)
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