Certain bacteria use the enzyme penicillinase to decom- pose penicillin and render it inactive. The Michaelis- Menten constants for this enzyme and substrate are Km = 5 × 10-5 mol L-ªand k, = 2 × 10³ s¯1. (a) What is the maximum rate of decomposition of peni- cillin if the enzyme concentration is 6 × 10-7 M? (b) At what substrate concentration will the rate of decomposition be half that calculated in part (a)?

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Certain bacteria use the enzyme penicillinase to decom-
pose penicillin and render it inactive. The Michaelis-
Menten constants for this enzyme and substrate are Km =
5 × 10-5 mol L-ªand k, = 2 × 10³ s¯1.
(a) What is the maximum rate of decomposition of peni-
cillin if the enzyme concentration is 6 × 10-7 M?
(b) At what substrate concentration will the rate of
decomposition be half that calculated in part (a)?
Transcribed Image Text:Certain bacteria use the enzyme penicillinase to decom- pose penicillin and render it inactive. The Michaelis- Menten constants for this enzyme and substrate are Km = 5 × 10-5 mol L-ªand k, = 2 × 10³ s¯1. (a) What is the maximum rate of decomposition of peni- cillin if the enzyme concentration is 6 × 10-7 M? (b) At what substrate concentration will the rate of decomposition be half that calculated in part (a)?
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