It appears that infection by Plasmodium is negative for Anopheles.  We also showed in class that the mosquito immune system can be upregulated to limit or terminate Plasmodium infection of these mosquitoes.  So why don’t we see natural selection to upregulate the mosquito’s immune system and get rid of that parasite?  Best explanation. Upregulating the immune system comes at the cost of shortening life span and thus (most probably) reproductive success Having a Plasmodium infection is negative for the mosquito, but it protects against much worse pathogens Upregulation of the immune system in Plasmodium leads to more rapid development of Plasmodium, causing even greater problems for Anopheles Statement is wrong. This upregulation was done with genetic engineering in a lab. Alleles to do something like that do not exist in nature

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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It appears that infection by Plasmodium is negative for Anopheles.  We also showed in class that the mosquito immune system can be upregulated to limit or terminate Plasmodium infection of these mosquitoes.  So why don’t we see natural selection to upregulate the mosquito’s immune system and get rid of that parasite?  Best explanation.

  • Upregulating the immune system comes at the cost of shortening life span and thus (most probably) reproductive success
  • Having a Plasmodium infection is negative for the mosquito, but it protects against much worse pathogens
  • Upregulation of the immune system in Plasmodium leads to more rapid development of Plasmodium, causing even greater problems for Anopheles
  • Statement is wrong. This upregulation was done with genetic engineering in a lab. Alleles to do something like that do not exist in nature
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