Zygote Oocyst Blood channel Liver cells- Cell nucleus- Sporozoites- Merozoites- Infected mosquito injects P. vivax sporozoites into a capillary as it feeds. 2 Sporozoites are carried to the liver, where they multiply in liver cells to form merozoites. The liver cells burst, releasing merozoites into liver blood channels. 3 The merozoites infect and differentiate in red blood cells (RBCS), becoming a ring form, then a trophozoite, then a schizont. The infected RBC breaks open, releasing merozoites. Some merozoites infect new RBCS, repeating this cycle. Others infect new RBCS then differentiate in them, forming male or female gametocytes. Another feeding mosquito ingests RBCS with gametocytes. 6 The gametocytes are released as the RBCS are digested. 6 The gametocytes become gametes, and fertilization occurs, forming a zygoto. The zygote becomes motile and penetrates the gut wall. 8 In the gut wall, the zygote forms an oocyst and multiplies asexually. FIGURE 25.9 LIfe Cycle of Plasmodlum vivax The oocyst releases sporozoites that infect the mosquito salivary glands. 2 Why do only female Anopheles mosquitoes transmit malaria?

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