Using the figure shown below, briefly explain the relationship between levels of HIV viral RNA, levels of CD4+ T cells, and health of the infected human.
Using the figure shown below, briefly explain the relationship between levels of HIV viral RNA, levels of CD4+ T cells, and health of the infected human.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Using the figure shown below, briefly explain the relationship between levels of HIV viral RNA, levels of CD4+ T cells, and health of the infected human.
![Primary
Infection
Death
1200
Acute HIV Infection
1000
107
Anti-HIV immune
Opportunistic
Infections
responses
800
Clinical Latency
106
600
Onset of
Symptoms
105
400-
104
AIDS
200
103
102
12
3
6
9
12
4
8
10
Weeks
Years
Time after infection
FIGURE 5.15 Typical time course of HIV infection and progression to disease. Patterns of CD4+ T-cell
decline and virus load vary greatly among patients. See also Fig. 5.16 for mortality as a function of initial viral
load. Some case definitions for AIDS specify a CD4+ count below 200 cells/µl (horizontal line). [From Coffin
et al. (1997, Fig. 5, p. 600).]
CD4+ T-cells (cells/ul)
HIV RNA (Copies/ml plasma)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F4dce494d-47c5-486e-a4c4-e68458c58e6c%2F66a4794c-8d74-4ce2-882d-110c56f67d19%2Fy2r0gp7_processed.png&w=3840&q=75)
Transcribed Image Text:Primary
Infection
Death
1200
Acute HIV Infection
1000
107
Anti-HIV immune
Opportunistic
Infections
responses
800
Clinical Latency
106
600
Onset of
Symptoms
105
400-
104
AIDS
200
103
102
12
3
6
9
12
4
8
10
Weeks
Years
Time after infection
FIGURE 5.15 Typical time course of HIV infection and progression to disease. Patterns of CD4+ T-cell
decline and virus load vary greatly among patients. See also Fig. 5.16 for mortality as a function of initial viral
load. Some case definitions for AIDS specify a CD4+ count below 200 cells/µl (horizontal line). [From Coffin
et al. (1997, Fig. 5, p. 600).]
CD4+ T-cells (cells/ul)
HIV RNA (Copies/ml plasma)
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