In the disease familial hypercholesterolemia (inherited tendency for high blood LDL cholesterol levels), the protein that helps clear cholesterol from the blood (called the LDL receptor) has a single amino acid that is different from the normal protein. This amino acid change greatly reduces the ability to clear cholesterol from the blood, resulting in high cholesterol levels and the risk of heart attack. Which of the following are different (compared to normal) in the person suffering from familial hypercholesterolemia? __The sequence of the mRNA that encodes for the LDL receptor. __The DNA sequence of the gene for the LDL receptor. __The presence of the gene for the LDL receptor. __The amino acid sequence of the LDL receptor.

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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In the disease familial hypercholesterolemia (inherited tendency for high blood LDL cholesterol levels), the protein that helps clear cholesterol from the blood (called the LDL receptor) has a single amino acid that is different from the normal protein. This amino acid change greatly reduces the ability to clear cholesterol from the blood, resulting in high cholesterol levels and the risk of heart attack.

Which of the following are different (compared to normal) in the person suffering from familial hypercholesterolemia?


__The sequence of the mRNA that encodes for the LDL receptor.
__The DNA sequence of the gene for the LDL receptor.
__The presence of the gene for the LDL receptor.
__The amino acid sequence of the LDL receptor.
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