Second base A UCU Phe UCC UUU UAU UGU Tyr Cys UUC UAC Ser UAA Stop UGA Stop A UGC UUA Leu UUG UCA UCG UAG Stop UGG Trp G CUU CCU CAU CGU His CUC Leu CUA CAC Pro CAA CCC CGC Arg CGA CCA CUG Gln CGG CCG CAG AUU AAU AGU Asn AAC ACU Ser AUC Ile A AUA AGC ACC Thr ACA AAA AGA AUG Met ACG Lys AAG AGG Arg GUU GCU GAU GGU Asp GAC GUC G GUA GCC Val GCA GGC Ala Gly GGA GAA Glu GAG GUG GCG GGG 15.10 The genetic code consists of 64 codons. First base Third base

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Hemoglobin is a complex protein that contains four polypeptide chains. The normal hemoglobin found in adults—called adult hemoglobin— consists of two alpha and two beta polypeptide chains, which are encoded by different loci. Sickle-cell hemoglobin, which causes sicklecell anemia, arises from a mutation in the beta chain of adult hemoglobin. Adult hemoglobin and sickle-cell hemoglobin differ in a single amino acid: the sixth amino acid from one end in adult hemoglobin is glutamic acid, whereas sickle-cell hemoglobin has valine at this position. After consulting the genetic code provided in Figure 15.10, indicate the type and location of the mutation that gave rise to
sickle-cell anemia.

Second base
A
UCU
Phe
UCC
UUU
UAU
UGU
Tyr
Cys
UUC
UAC
Ser
UAA Stop UGA Stop A
UGC
UUA
Leu
UUG
UCA
UCG
UAG Stop UGG Trp G
CUU
CCU
CAU
CGU
His
CUC
Leu
CUA
CAC
Pro
CAA
CCC
CGC
Arg
CGA
CCA
CUG
Gln
CGG
CCG
CAG
AUU
AAU
AGU
Asn
AAC
ACU
Ser
AUC Ile
A
AUA
AGC
ACC
Thr
ACA
AAA
AGA
AUG Met ACG
Lys
AAG
AGG
Arg
GUU
GCU
GAU
GGU
Asp
GAC
GUC
G
GUA
GCC
Val
GCA
GGC
Ala
Gly
GGA
GAA
Glu
GAG
GUG
GCG
GGG
15.10 The genetic code consists of 64 codons.
First base
Third base
Transcribed Image Text:Second base A UCU Phe UCC UUU UAU UGU Tyr Cys UUC UAC Ser UAA Stop UGA Stop A UGC UUA Leu UUG UCA UCG UAG Stop UGG Trp G CUU CCU CAU CGU His CUC Leu CUA CAC Pro CAA CCC CGC Arg CGA CCA CUG Gln CGG CCG CAG AUU AAU AGU Asn AAC ACU Ser AUC Ile A AUA AGC ACC Thr ACA AAA AGA AUG Met ACG Lys AAG AGG Arg GUU GCU GAU GGU Asp GAC GUC G GUA GCC Val GCA GGC Ala Gly GGA GAA Glu GAG GUG GCG GGG 15.10 The genetic code consists of 64 codons. First base Third base
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