In recent years, the country of Zambia in Africa has had increasing cases of malaria. If 8 % of the population is born with a severe form of sickle-cell anemia (ss), what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene, under the Hardy-Weinberg assumption

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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In recent years, the country of Zambia in Africa has had increasing cases of malaria. If 8 % of the population is born with a severe form of sickle-cell anemia (ss), what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene, under the Hardy-Weinberg assumption?

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Introduction:

Hardy -Weinberg (H-W) provided a null hypothesis for the population not evolving. If all H-W assumptions were met, the allele frequencies and genotype frequencies can be linked by H-W equations. The following assumptions should be true for that population:

  1. The population should be large.
  2. There should be no mutations happening
  3. There should be no immigration or emigration, hence no gene flow.
  4. The mating between individuals should be random without sexual preferences
  5. Natural selection should be absent.
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