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In nucleophilic acyl substitution, addition to the carbonyl by a nucleophile is followed by loss of the leaving group. O loss of the leaving group is followed by rearrangement of the carbocation. ester hydrolysis is followed by deprotonation. O protonation of the carbonyl is followed immediately by loss of the leaving grou O an SN2 reaction occurs.

In nucleophilic acyl substitution, addition to the carbonyl by a nucleophile is followed by loss of the leaving group. O loss of the leaving group is followed by rearrangement of the carbocation. ester hydrolysis is followed by deprotonation. O protonation of the carbonyl is followed immediately by loss of the leaving grou O an SN2 reaction occurs.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question 23 In nucleophilic acyl substitution, O addition to the carbonyl by a nucleophile is followed by loss of the leaving group. O loss of the leaving group is followed by rearrangement of the carbocation. O ester hydrolysis is followed by deprotonation. O protonation of the carbonyl is followed immediately by loss of the leaving grour O an SN2 reaction occurs.
Transcribed Image Text:Question 23 In nucleophilic acyl substitution, O addition to the carbonyl by a nucleophile is followed by loss of the leaving group. O loss of the leaving group is followed by rearrangement of the carbocation. O ester hydrolysis is followed by deprotonation. O protonation of the carbonyl is followed immediately by loss of the leaving grour O an SN2 reaction occurs.
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