Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. Some individuals who are homozygous for this autosomal recessive gene experience only skin discoloration and joint pain, others experience heart disease in addition to the skin discoloration, still other individuals suffer also suffer from diabetes, severe heart disease, and liver damage. Name and define this genetic phenomenon and explain how it relates to this specific genetic situation described above.

Q: Fanconi anemia is an autosomal recessive disease caused by a mutation in a single gene. It's a…

A: The objective of the question is to understand how we can determine from a pedigree that Fanconi…

Q: Phenylketonuria (PKU) is an autosomal recessive disease that results from a defect in an enzyme that…

A: Phenylketonuria is an inborn error of metabolism which happened due to decreased or low metabolism…

Q: estions below all refer to the following pedigree. The locus for allele D/d determines how cilia on…

A: It is evident that the trait is not sex-linked because:-   In the case of Y-linked disorders, only…

Q: What are the possible genotypes for the following wizards for the MC1R gene? I:…

A: Genetic Inheritance: The genes from parents regulating different traits are passed down to offspring…

Q: Wilson's disease is an inherited disorder caused by a mutation in the ATP7B gene. Individuals…

A: From the given pedigreees we can identify the mode of inheritance of Wilson's disease. In both…

Q: Mutation that results in death before the age of reproduction Mutation that results in an inactive…

A: Dominant mutations are those mutations which arise from the mutation of single copy of  dominant…

Q: The allele for albinism is recessive to the allele for normal skin pigmentation. All individuals who…

A: An inherited disorder that presents with little or no melanin production, which results in either…

Q: The questions below all refer to the following pedigree. The locus for allele D/d determines how…

A:

Q: Human growth hormone (HGH) is necessary for growth during human adolescence. Pituitary dwarfism is a…

A: Growth hormone (GH), also known as somatotropin or human growth hormone (hGH or HGH) , is a peptide…

Q: ake the example of B-thalassemia, an autosomal recessive genetic disease that particularly affects…

A: A point mutation is a change in the single nucleotide pair of DNA.

Q: Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a…

A: According to Hardy Weinberg`s equilibrium p2 + q2 +2pq =1 and p+q=1 p = frequency of the dominant…

Q: A couple named Bob and Brené have 2 children: Angela (female) and Arnold (male). Arnold has sickle…

A: Pedigree analysis is a diagrammatic representation of an individual's family tree that is used to…

Q: A possible explanation for the increased incidence of Tay-Sachs disease among Ashkenazi Jews is

A: Tay Sachs is a rare autosomal recessive disorder that causes mental and physical disabilities…

Q: A form of hemophilia is caused by a sex-linked (X-linked) recessive gene. A phenotypically normal…

A: 50 percent chances.

Q: Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb…

A: Mutations are alterations in the DNA sequence of an organism. Small changes, such as adding or…

Q: Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood…

A: HbA encodes normal phenotype. This allele is dominant over HbS allele.

Q: Wilson’s disease is an inherited disorder in which there is too much copper in the body’s tissue. It…

A: A pedigree chart is a graphic that depicts the incidence and emergence of phenotypes of a certain…

Q: Cystic fibrosis is a disease that is passed down through the generations. The recessive alleles for…

A: Genes carry the traits from one generation to another. Genes that code for different forms of a…

Q: Lesch-Nyhan syndrome is due to a mutation in a gene that encodesa protein called…

A: Pedigree or family tree is a representation of an individual in a family or close relatives that…

Q: Assuming that no new mutation was present in their daughter, offer a genetic explanation for her…

A: Haemophilia is an X linked recessive disorder. In such cases, males (XY) With one copy of defected…

Q: In humans, hemophilia is an X-linked recessive disorder that affects the gene for factor VIII…

A: Genetic disorders can be inherited either through recessive or dominant mutation. In case of a gene…

Q: Given that this mutated allele will cause disease and death in individuals, what would you predict…

A: Sickel cell anemia is an autosomal recessive genetic disorder that affects the shape of red blood…

Q: Hemophilia is a recessive sex-linked trait in humans.  Sickle-cell anemia is a recessive trait on an…

A: Hemophilia is X linked recessive disorder in which blood continuously flows because of absence of…

Q: Bart and Jenny, have been arguing about the cause of their baby's aneuploid condition. Bart was 5…

A: X Linked Inheritance When the disease-causing gene or allele is present on the Sex chromosome…

Q: Please find an Image/Graphic to represent sickle cell disease: Use at least two different images to…

A: A picture or graphic must be found to depict sickle cell illness. To better comprehend the…

Q: Humans who have an abnormally high level of cholesterol are said to suer from familial…

A: The way the body processes cholesterol is affected by familial hypercholesterolemia. People with…

Q: If one person with the trait of Huntington's disease (H h) has 2 children with a partner who does…

A: INTRODUCTION Huntington's disease It is an inheritable disease in which nerve cells in the brain…

Q: The attached image is a pedigree of a family with a history of sickle cell anemia (the individuals…

A: Sickle cell anemia is a genetic condition caused by a mutation in the gene that codes for…

Q: Albinism is inherited through a recessive allele (a). Juan has normal skin color. His Mom and Dad…

A: Genotype means the alleles constituting the genetic composition and responsible for the expressing…

Q: Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood…

A: HbS encodes sickle shaped red blood cell. It is recessive to the HbA allele. HbA allele encodes…

Hematology

Hematology is the branch of biology. Hematology is the medical field that deals with the treatment of blood disorders and cancers, such as hemophilia, leukemia, lymphoma, and sickle-cell anemia. Hematologists and hematopathologists are medical professionals who specialize in illnesses of the blood and its components.