H H. H-C-OH Н—С—он C=0 HO-C-H НО—С—Н phosphohexose isomerase Н—с—ОН H-C-OH Н—С—ОН Н—С—ОН CH2OPO3 CH2OPO3 Glucose 6-phosphate Fructose 6-phosphate

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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In the glycolytic pathway, a six-carbon sugar (fructose 1,6-bisphosphate) is cleaved to form two three-carbon sugars, which undergo further metabolism . In this pathway, an isomerization of glucose 6-phosphate to
fructose 6-phosphate (shown below) occurs two steps before the cleavage reaction (the intervening step is phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate ). What does the isomerization step accomplish from a chemical perspective? (Hint: Consider what might happen if the C—C bond cleavage were to proceed without the preceding isomerization.)

H
H.
H-C-OH
Н—С—он
C=0
HO-C-H
НО—С—Н
phosphohexose
isomerase
Н—с—ОН
H-C-OH
Н—С—ОН
Н—С—ОН
CH2OPO3
CH2OPO3
Glucose 6-phosphate
Fructose 6-phosphate
Transcribed Image Text:H H. H-C-OH Н—С—он C=0 HO-C-H НО—С—Н phosphohexose isomerase Н—с—ОН H-C-OH Н—С—ОН Н—С—ОН CH2OPO3 CH2OPO3 Glucose 6-phosphate Fructose 6-phosphate
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