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RI H C H 10: N NH₂ :0: C H N O

RI H C H 10: N NH₂ :0: C H N O

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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on 2 of 25 Draw curved arrows to show reaction of NADPH with mevaldehyde. Select Draw Templates Groups More R1 H C H N 0 : 0: NH₂ :0: Erase H Draw the intermediate and draw hydrogens on oxygen and nitrogen where applicable. Then draw curved arrows to form mevalonate. Select Draw Templates Groups More ////// C H N 0 Erase
Transcribed Image Text:on 2 of 25 Draw curved arrows to show reaction of NADPH with mevaldehyde. Select Draw Templates Groups More R1 H C H N 0 : 0: NH₂ :0: Erase H Draw the intermediate and draw hydrogens on oxygen and nitrogen where applicable. Then draw curved arrows to form mevalonate. Select Draw Templates Groups More ////// C H N 0 Erase
The thioester (S)-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) is reduced by HMG-CoA reductase to form the intermediate mevaldehyde, which is shown in an abbreviated form in the image. Draw the intermediate formed from reaction of mevaldehyde with NADPH and use curved arrows to show electron movement. Be sure to show the R and 'R groups (Located in the Groups menu), charges, and non-bonding electron pairs as needed. H H R₁ NADPH NH₂ H Mevaldehyde Draw curved arrows to show reaction of NADPH with mevaldehyde. Select Draw Templates Groups More H₂O* H₂O u Erase R₁ NADP' NH₂ :OH H H Mevalonate Draw the intermediate and draw hydrogens on oxygen and nitrogen where applicable. Then draw curved arrows to form mevalonate. Select Draw Templates Groups More Erase
Transcribed Image Text:The thioester (S)-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) is reduced by HMG-CoA reductase to form the intermediate mevaldehyde, which is shown in an abbreviated form in the image. Draw the intermediate formed from reaction of mevaldehyde with NADPH and use curved arrows to show electron movement. Be sure to show the R and 'R groups (Located in the Groups menu), charges, and non-bonding electron pairs as needed. H H R₁ NADPH NH₂ H Mevaldehyde Draw curved arrows to show reaction of NADPH with mevaldehyde. Select Draw Templates Groups More H₂O* H₂O u Erase R₁ NADP' NH₂ :OH H H Mevalonate Draw the intermediate and draw hydrogens on oxygen and nitrogen where applicable. Then draw curved arrows to form mevalonate. Select Draw Templates Groups More Erase
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