High levels of pyruvate: activate pyruvate dehydrogenase kinase and consequently activate the pyruvate dehydrogenase complex. inhibit pyruvate dehydrogenase kinase and therefore increase the activity of the pyruvate dehydrogenase complex. inhibit pyruvate dehydrogenase phosphatase and therefore enhance the activity of pyruvate dehydrogenase complex. activate pyruvate dehydrogenase phosphatase and hence inhibit the activity of pyruvate dehydrogenase complex. activate pyruvate dehydrogenase phosphatase and therefore promote phosphorylation of the pyruvate dehydrogenase complex.

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Organic Chemistry of Metabolic Pathways

Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.

Glucogenesis

Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general  definition for glucogenesis or gluconeogenesis is as follows,