Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Transcribed Image Text:TULIVU amica, canie.
Glucose uptake
100.
50
25
O 1.5mM
6mM
K
3mM
1 2 3 4 5 6 7
Extracellular conc. of Glucose
O 12mM
8
Can't predict from the data provided
9
Transcribed Image Text:Through your biotechnology research
project at the Tiger One Brewery, you
engineered a glucose transporter in a
yeast strain in order to increase its rate of
fermentation. Your colleague recorded the
glucose uptake data shown below from
the yeast strain you developed and to your
surprise, you found out that your
engineered glucose transporter has three-
fold more affinity to glucose compared to
the wild-type (native/unmodified) glucose
transporter. From the figure below, can
you predict the Km of the wild-type
glucose transporter?
Note: The Vmax of the wildtype and
engineered transporters are the same in
the experimental setup, and the plot
below is the data of your engineered
glucose transporter and NOT the wildtype
(native/unmodified) transporter.
Glucose uptake
100..
50-
25
Expert Solution
Step 1: Michelias Menton graph
The picture shows the relationship between glucose uptake and extracellular glucose concentration. With increase in extracellular glucose concentration, the increase in glucose uptake occurs in cell up to a saturation point.
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