Glucose-6-phosphate dehydrogenase (G6PD) is a critical enzyme involved in the metabolism of glucose,especially in red blood cells. Deficiencies in the enzymeare the most common human enzyme defect and occurat a high frequency in certain populations of East Africanchildren.a. Offer one hypothesis for the high incidence of G6PDmutations in East African children.b. How would you test your hypothesis further?c. Scores of different G6PD mutations affecting enzyme function have been found in human populations.Offer one explanation for the abundance of differentG6PD mutations.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.