Glomerular filtration rate (GFR) is the most important parameter of renal function assessed in renal transplant recipients. Although inulin clearance is regarded as the gold standard measure of GFR, its use in clinical practice is limited. Krieser et al. examined the relationship between the inverse of Cystatin C (a cationic basic protein measured in mg/L) and inulin GFR as measured by technetium radionuclide labeled diethylenetriamine penta-acetic acid) (DTPA GFR) clearance (ml/min/1.73 m2). The results of 27 tests are shown in the following table: DTPA GFR 1/Cystatin C DTPA GFR 1/Cystatin C 18 0.213 21 0.265 21 0.446 23 0.203 27 0.369 27 0.568 30 0.382 32 0.383 32 0.274 32 0.424 36 0.308 37 0.498 41 0.398 42 0.485 42 0.427 43 0.562 43 0.463 48 0.549 48 0.538 51 0.571 55 0.546 58 0.402 60 0.592 62 0.541 67 0.568 68 0.800 68 0.667 Use the data to solve the following: 4. Test if there is a significant relationship between variables at alpha = 0.05 (show 6 steps). 5. Compute for the regression model and predict the cystatin c if DTPA GFR is 50. (Use two decimal places).

Glomerular filtration rate (GFR) is the most important parameter of renal function assessed in renal transplant recipients. Although inulin clearance is regarded as the gold standard measure of GFR, its use in clinical practice is limited. Krieser et al. examined the relationship between the inverse of Cystatin C (a cationic basic protein measured in mg/L) and inulin GFR as measured by technetium radionuclide labeled diethylenetriamine penta-acetic acid) (DTPA GFR) clearance (ml/min/1.73 m2). The results of 27 tests are shown in the following table: DTPA GFR 1/Cystatin C DTPA GFR 1/Cystatin C 18 0.213 21 0.265 21 0.446 23 0.203 27 0.369 27 0.568 30 0.382 32 0.383 32 0.274 32 0.424 36 0.308 37 0.498 41 0.398 42 0.485 42 0.427 43 0.562 43 0.463 48 0.549 48 0.538 51 0.571 55 0.546 58 0.402 60 0.592 62 0.541 67 0.568 68 0.800 68 0.667 Use the data to solve the following: 4. Test if there is a significant relationship between variables at alpha = 0.05 (show 6 steps). 5. Compute for the regression model and predict the cystatin c if DTPA GFR is 50. (Use two decimal places).

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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[Part2] Glomerular filtration rate (GFR) is the most important parameter of renal function assessed in renal transplant recipients. Although inulin clearance is regarded as the gold standard measure of GFR, its use in clinical practice is limited. Krieser et al. examined the relationship between the inverse of Cystatin C (a cationic basic protein measured in mg/L) and inulin GFR as measured by technetium radionuclide labeled diethylenetriamine penta-acetic acid) (DTPA GFR) clearance (ml/min/1.73 m2). The results of 27 tests are shown in the following table:

DTPA GFR 1/Cystatin C

18 0.213

21 0.265

21 0.446

23 0.203

27 0.369

27 0.568

30 0.382

32 0.383

32 0.274

32 0.424

36 0.308