Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying table (based on data from “Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme”, by MacGregor et al., BMJ, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril has an effect on systolic blood pressure? Explain why statistical methods from Z-interval, Z-test, T-interval or T-test –cannot be used for this problem. Then, use the sign test to conduct the required test in R studio. Please show your work.
4.
Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying table (based on data from “Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme”, by MacGregor et al., BMJ, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril has an effect on systolic blood pressure? Explain why statistical methods from Z-interval, Z-test, T-interval or T-test –cannot be used for this problem. Then, use the sign test to conduct the required test in R studio. Please show your work.
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