For each DNA repair process in column I, list all characteristics fromcolumn II that correctly describe that process.I(a) Nucleotide excision repair(b) Photoreactivation(c) Base excision repair(d) Recombinational repair(e) SOS-driven error-prone repair(f) Alkyltransferase repair(g) Mismatch repair(h) Double-strand break repairII1. RecA protein participates.2. Damaged nucleotides are removed by nick translation.3. A free radical mechanism is involved.4. The repair enzyme functions only once.5. The key enzyme contains a bound folate cofactor.6. No bases or nucleotides are removed from the DNA.7. Deficiency of this enzyme in humans greatly increases the risk of skincancer.8. This system is chiefly responsible for the mutagenic effect of ultravioletlight.9. This process begins with cleavage of two phosphodiester bonds.10. This process begins up to 1 kbp away from the site to be repaired.11. DNA ligase catalyzes the final reaction.12. This process also occurs in meiotic recombination.13. Replication fork regression might occur during this process.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
For each DNA repair process in column I, list all characteristics from
column II that correctly describe that process.
I
(a)
(b) Photoreactivation
(c) Base excision repair
(d) Recombinational repair
(e) SOS-driven error-prone repair
(f) Alkyltransferase repair
(g) Mismatch repair
(h) Double-strand break repair
II
1. RecA protein participates.
2. Damaged nucleotides are removed by nick translation.
3. A free radical mechanism is involved.
4. The repair enzyme functions only once.
5. The key enzyme contains a bound folate cofactor.
6. No bases or nucleotides are removed from the DNA.
7. Deficiency of this enzyme in humans greatly increases the risk of skin
cancer.
8. This system is chiefly responsible for the mutagenic effect of ultraviolet
light.
9. This process begins with cleavage of two phosphodiester bonds.
10. This process begins up to 1 kbp away from the site to be repaired.
11. DNA ligase catalyzes the final reaction.
12. This process also occurs in meiotic recombination.
13. Replication fork regression might occur during this process.
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