. For each DNA repair process in column I, list all characteristics from col- umn II that correctly describe that process. I (a) Nucleotide excision repair (b) Photoreactivation (c) Base excision repair (d) Recombinational repair (e) SOS-driven error-prone repair (f) Alkyltransferase repair (g) Mismatch repair (h) Double-strand break repair II 1. RecA protein participates. 2. Damaged nucleotides are removed by nick translation. 3. A free radical mechanism is involved. 4. The repair enzyme functions only once. 5. The key enzyme contains a bound folate cofactor. 6. No bases or nucleotides are removed from the DNA. 7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer. 8. This system is chiefly responsible for the mutagenic effect of ultravioletlight. 9. This process begins with deavage of two phosphodiester bonds. 10. This process begins up to 1 kbp away from the site to be repaired. 11. DNA ligase catalyzes the final reaction. 12. This process also occurs in meiotic recombination. 13. Replication fork regression might occur during this process.

. For each DNA repair process in column I, list all characteristics from col- umn II that correctly describe that process. I (a) Nucleotide excision repair (b) Photoreactivation (c) Base excision repair (d) Recombinational repair (e) SOS-driven error-prone repair (f) Alkyltransferase repair (g) Mismatch repair (h) Double-strand break repair II 1. RecA protein participates. 2. Damaged nucleotides are removed by nick translation. 3. A free radical mechanism is involved. 4. The repair enzyme functions only once. 5. The key enzyme contains a bound folate cofactor. 6. No bases or nucleotides are removed from the DNA. 7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer. 8. This system is chiefly responsible for the mutagenic effect of ultravioletlight. 9. This process begins with deavage of two phosphodiester bonds. 10. This process begins up to 1 kbp away from the site to be repaired. 11. DNA ligase catalyzes the final reaction. 12. This process also occurs in meiotic recombination. 13. Replication fork regression might occur during this process.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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During your first year, you took Foundations in Biology for Biomedical Sciences 2 (or equivalent), and were introduced to many important biology concepts that you will use throughout your career. These skills would allow you to solve problems such as: (a) Provide the sequence of the DNA complementary to the following strand (please write it in the 3' to 5' orientation). 5' - СТAGCTAСTGACT - 3'
For each DNA repair process in column I, list all characteristics fromcolumn II that correctly describe that process.I(a) Nucleotide excision repair(b) Photoreactivation(c) Base excision repair(d) Recombinational repair(e) SOS-driven error-prone repair(f) Alkyltransferase repair(g) Mismatch repair(h) Double-strand break repairII1. RecA protein participates.2. Damaged nucleotides are removed by nick translation.3. A free radical mechanism is involved.4. The repair enzyme functions only once.5. The key enzyme contains a bound folate cofactor.6. No bases or nucleotides are removed from the DNA.7. Deficiency of this enzyme in humans greatly increases the risk of skincancer.8. This system is chiefly responsible for the mutagenic effect of ultravioletlight.9. This process begins with cleavage of two phosphodiester bonds.10. This process begins up to 1 kbp away from the site to be repaired.11. DNA ligase catalyzes the final reaction.12. This process also occurs in meiotic recombination.13.…
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RNA polymerases generally require a primer to begin transcription. (T) (F) The Death Cap Mushroom Amanita phalloides is toxic because of its ability to produce alpha-amanitin, which is an inhibitor of RNA Polymerases I and III. (T) (F) In bacteria, transcription and translation can occur simultaneously. (T) (F) In eukaryotes, transcription and translation can occur simultaneously (T) (F) RNA polymerase II has no form of proofreading activity. (T) (F) Sigma factors specify binding of bacterial RNA Polymerases to specific promoters (T) (F) An E. coli strain with mutations in genes encoding both the dam methylase and the RecA protein would likely be inviable (dead) (T) (F) An E. coli culture grown in a pure (100%) N2 atmosphere would likely have a lower rate of mutations than a culture grown under normal conditions (~30% O2 and 70% N2) (T) (F) Non-homologous end joining repairs double strand DNA breaks with no loss of information, restoring the original…
1) The function of ligase is to seal nicks in the backbone of a DNA strand. The function of AP endonuclease is to create a nick in the backbone of a DNA molecule adjacent to an apurinic site, which allows DNA polymerase II access to the DNA to repair the damage and prevent a mutation resulting from the use of a damaged or erroneous strand of DNA as template during DNA replication. Why doesn't ligase simply seal up the nicks the AP endonuclease introduces before DNA pol II can do anything?