You start with a relaxed DNA plasmid that is 1000bp in length. a). What is the starting linking number, twist, and writhe? Assume 10bp per helical turn.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
icon
Concept explainers
Question
8. Please help answer this question and show all work, thank you so much.
8). You start with a relaxed DNA plasmid that is 1000bp in length.
a). What is the starting linking number, twist, and writhe? Assume 10bp per helical turn.
b). Addition of magic "compound X" alters the DNA helix pitch from 10bp per helical turn
to 4bp per helical turn. What is the new linking number, twist, and writhe?
c). Do you expect this new molecule to be larger (in terms of the volume it occupies) or
smaller than the original molecule?
Transcribed Image Text:8). You start with a relaxed DNA plasmid that is 1000bp in length. a). What is the starting linking number, twist, and writhe? Assume 10bp per helical turn. b). Addition of magic "compound X" alters the DNA helix pitch from 10bp per helical turn to 4bp per helical turn. What is the new linking number, twist, and writhe? c). Do you expect this new molecule to be larger (in terms of the volume it occupies) or smaller than the original molecule?
Expert Solution
steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Bacterial genomics
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education