For an enzyme following Michaelis-Menten kinetics and in the presence of 300 mM of its substrate, predict how an additional 50 mM of substrate will alter this enzyme's kinetics if added to the reaction (350 mM total substrate now in the reaction mixture). Substrate concentration [S] Reaction velocity (v;) 5 mM 10 10 mM 25 25 mM 50 50 mM 75 100 mM 90 200 mM 100 O a The reaction velocity (v;) but not Km will increase O b. Neither the reaction velocity (v;) nor Km will increase O c. Km will increase but the reaction velocity (v;) will stay the same O d. Both the reaction velocity (v;) and Km will increase
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
![For an enzyme following Michaelis-Menten kinetics and in the presence of 300 mM of its substrate, predict how an
additional 50 mM of substrate will alter this enzyme's kinetics if added to the reaction (350 mM total substrate now in the
reaction mixture).
Substrate concentration [S]
Reaction velocity (v;)
5 mM
10
10 mM
25
25 mM
50
50 mM
75
100 mM
90
200 mM
100
The reaction velocity (v;) but not Km will increase
а.
O b. Neither the reaction velocity (v;) nor Km will increase
O c. Km will increase but the reaction velocity (v;) will stay the same
O d. Both the reaction velocity (v;) and Km will increase](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F4f9c5faa-1e54-4dbe-8532-7f5348c7cfbf%2F6b058fd7-15c5-4655-9d0a-50aedf53d51b%2Fe6qzyc_processed.png&w=3840&q=75)
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