Folic acid is synthesized in bacteria as dihydrofolate, in a pathway startingfrom guanosine triphosphate. In this pathway, C-8 is lost as formate. Fromthe structural similarities between guanine and pterin, predict which carbonand nitrogen atoms of GTP are the precursors to N-1, C-2, C-4, N-5, C-7,N-8, and C-9 of dihydrofolate. 510PABAGIUHN 47H,N2 N1Dihydrofolate7HN8.H,N 2 N43PP.PO5'3 2ÓH ÓHGTPZI

Dihydrofolic acid is a folic acid derivative which is converted to tetrahydrofolic acid by…

Answered: Folic acid is synthesized in bacteria…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Draw the mechanism for the hydrolysis of the peptide bonds of aspartame. Draw all arrows
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UDP-glucuronosyltransferase enzymes bind the organic compound UDP-glucuronic acid (UDP-GA) in order to catalyse the transfer of a glucuronic acid group from UDP-GA to a drug molecule, releasing UDP from the active site as a product. UDP is then regenerated by the activity of another enzyme. What terms could be used to describe UDP-GA?
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In the salvage of purines, hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is responsible for which of the following processes? Conversion of hypoxanthine to xanthine Conversion of adenine to adenosine monophosphate (AMP) Conversion of guanine to guanosine monophosphate (GMP) Conversion of inosine monophosphate to inosine
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the structures of chymotrypsin and other serine proteases revealed that the active sites of these enzymes shared a particular sterochemical arrangement of residues crucial to their activity. This came to be known as the catalytic triad, as it consisted of the oponyomous serine (Ser) residue, along with a histidine (His) and an aspartate (Asp) residue. Which of the following would result in the greatest decrease in function of the catalytic triad found in serine proteases? O Mutation to Ser, Cys, Asp O Mutation to Ser, His, Asp O Mutation to Cys, His, Asp O Mutation to Ser, His, Glu
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