Acetylcholinesterase (ACHE) is a key enzyme involved in the transmission of nerve impulses. The function of ACHE Is to breakdown the neurotransmitter acetylcholine. ACHE is related to the serine proteases and contains the catalytic triad Glu-327, His-440 and Ser-200. The enzyme is the target of several classes of insecticides. Based on what you have learned about the serine proteases, the insecticide below most likely inhibits ACHE by? OCH3 CH30 NO2 O A. functioning as a competitive inhibitor for substate. O B. disrupting the H-bonding between Ser-200 and His-440. O C. functioning as a phosphonate transition state analog. O D. functioning as an irreversible inhibitor by forming a covalent bond with Ser-200. O E. functioning as a irreversible inhibitor forming a covalent bond with His-440.
Enzyme kinetics
In biochemistry, enzymes are proteins that act as biological catalysts. Catalysis is the addition of a catalyst to a chemical reaction to speed up the pace of the reaction. Catalysis can be categorized as either homogeneous or heterogeneous, depending on whether the catalysts are distributed in the same phase as that of the reactants. Enzymes are an essential part of the cell because, without them, many organic processes would slow down and thus will affect the processes that are important for cell survival and sustenance.
Regulation of Enzymes
A substance that acts as a catalyst to regulate the reaction rate in the living organism's metabolic pathways without itself getting altered is an enzyme. Most of the biological reactions and metabolic pathways in the living systems are carried out by enzymes. They are specific for their works and work in particular conditions. It maintains the best possible rate of reaction in the most stable state. The enzymes have distinct properties as they can proceed with the reaction in any direction, their particular binding sites, pH specificity, temperature specificity required in very few amounts.
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