Answered: Figure Q6-4 Two rounds of mutagenesis…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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After treating cells with a chemical mutagen, you
isolate two mutants. One carries alanine and the other
carries methionine at a site in the protein that normally
contains valine (Figure Q6–4). After treating these two
mutants again with the mutagen, you isolate mutants from
each that now carry threonine at the site of the original
valine (Figure Q6–4). Assuming that all mutations involve
single-nucleotide changes, deduce the codons that are
used for valine, methionine, threonine, and alanine at the
affected site. Would you expect to be able to isolate valine-
to-threonine mutants in one step?

Figure Q6-4 Two rounds of
mutagenesis and the altered
amino acids at a single position in
a protein (Problem 6-9).
first
Ala
second
treatment
treatment
Val
Thr
Met

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