In E. coli, a variety of mutator strains have been identified inwhich the spontaneous rate of mutation is much higher than innormal strains. Make a list of the types of abnormalities thatcould cause a strain of bacteria to become a mutator strain. Whichabnormalities do you think would give the highest rate of spontaneousmutation?
Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
In E. coli, a variety of mutator strains have been identified in
which the spontaneous rate of mutation is much higher than in
normal strains. Make a list of the types of abnormalities that
could cause a strain of bacteria to become a mutator strain. Which
abnormalities do you think would give the highest rate of spontaneous
mutation?
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