why would a mutation complex 1 usually not result in immediate death ? And while blocking complex IV can result in immediate death ?

Q: O a base substitution in an intron 5' splice site O a frameshift in an exon O a missense in an exon…

A: The answer to the question is  A frameshift in exon

Q: If you were to design an experiment to get p53 back into cancer cells, how would you go about that…

A: p53 Is a nuclear transcription factor that promotes apoptosis. Because over 50% of human cancers…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: Is chromosome deletion equivalent to a frameshift mutation (discussed in Chapter 13)? Why or why…

A: A frameshift mutation is occurred due to insertion or deletion of a number of nucleotides which are…

Q: The rb gene encodes a protein that inhibits E2F, a transcriptionfactor that activates several genes…

A: Abnormal and unnecessary growth of cells termed cancer. Mutations in DNA causes cancer. In the…

Q: What is the long term and short term effects of mutation on coding and non-coding DNA, the amount of…

A: A mutation is a change in the nucleotide sequence of an organism's genome, virus, or…

Q: Why are diseases due to microsatellite amplification, even though they have a monogenic pattern of…

A: The classical inheritance is the type of inheritance pattern in which mendelian laws are followed…

Q: Which step of the Central Dogma is responsible for transmission of genetic information from…

A: The central dogma is a process through which the information present in the DNA is converted into…

Q: List examples of paracrine chemical messengers that playa role in modulating pain or are peptide…

A: paracrine chemical messenger act on adjacent cells.

Q: Explain about the epigenetic differences ?

A: Introduction Expression of gene is highly under control by various mechanisms such as histone…

Q: When an injury occurs to the skin, the epithelial cells near the wound are signaled to react (by…

A: Introduction:- Chromosomes are the most condensed and compact structures that are made up of DNA…

Q: Although each cell in your body contains the same set of genes, the genes that are “turned on”…

A: DISCLAIMER FOR MULTIPLE   Since you have asked multiple question, we will solve the first question…

Q: How many protein coding genes would expect to be affected if the mutations are distributed randomly?

A: Due to metabolic mistakes, radiation exposure, and environmental variables, DNA experiences numerous…

Q: Is the mutation in the sickle cell gene a point mutation or a frameshift mutation?

A: Point mutations are a large category of mutations that describe a change in single nucleotide of…

Q: Describe the function of CYP3A4?

A: Answer- CYP3A4 or cytochrome P450 3A4 is a human enzyme that is present and synthesized in the…

Q: Explain what is c-myc translocation and why it results in overexpression of c-myc. What is the role…

A: Epstein-Barr virus or EBV is one of the most common viruses found in the human body. They pass from…

Q: The most prominent mutation of ERBB2 in breast cancer is L755S.  What kind of mutation is this?  Is…

A: Mutation is the change in structure of a gene, which results in variation. These variations can be…

Q: What is enzyme adaptation? From a genetic point of view, how does it occur?

A: Enzymes are catalysts that speed up chemical reactions without being used up in the process”. A…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: Hydroxylamine (HA) causes only G • C → A • T transitions in DNA. Will HA produce nonsense mutations…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: How do these engineered nucleases effect a change in the genomic DNA sequence?

A: Genome editing is a technique used to precisely and efficiently modify DNA within a cell. It…

Q: Explain the difference between a gain-of-functionmutation and a dominant-negative mutation. Why…

A: A mutation is referred to as a change in an organism's DNA sequence. Mutations can occur as a result…

Q: Which form of Retinoblastoma typically results in unilateral disease and exhibits 2-hit mutational…

A: Retinoblastoma is a cancer that affects the eyes. It is specifically a cancer of retinal layer of…

Q: What is the key component(s) of usher syndrome. A) The Effect of mutation and Hot-spots of mutation?…

A: Usher syndrome is a hereditary autosomal disorder passed down through the generations from parent to…

Q: Mutations within the genes for ARSs, are known to be cause certain human maladies, such as the…

A: ARS is an amino-acyl tRNA synthetase that catalyzes the addition of amino acid to the acceptor stem…

Q: [GAINI- is a protein coding gene that regulates cardiomyocyte metabolism in patients with heart…

A: Cardiovascular refers to the circulatory system. The circulatory system, which includes the heart…

Q: What type of mutation is sickle cell anemia? Explain the molecular basis of sickle cell anemia.

A: Sickle cell anemia is an abnormal condition that arises due to the mutation in the beta-globin chain…

Q: A gene, which we will call gene C, can be epigenetically modified in such a way that its expression…

A: Introduction: Gene is the structural and functional unit of inheritance or heredity which transfers…

Q: As discussed, the overall rate of mutations in humans is estimated to be about 1 × 10−8 mutations…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Acquired mutation in the p53 gene is the most common genetic alteration found in human cancer (> 50%…

A: The correct option is F. Transcription factor

Q: A mutation takes place that switches a codon from ACG to ACA. What type of mutation is this? A)…

A: A mutation is a random change in the DNA sequence.

Q: Based on Figure 17-35, write a sentence stating howtranslocation can lead to cancer. Can you think…

A: Translocations were discovered cytologically for the first time in the late nineteenth and early…

Q: Let’s suppose you were interested in developing drugs to preventepigenetic changes that may…

A: Genes are basic physical and functional unit of heredity. It is a part of DNA that has instruction…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.