As discussed, the overall rate of mutations in humans is estimated to be about 1 × 10−8 mutations per base pair per generation. How many new mutations would you expect each person to carry, on average, based on this mutation rate? Other studies have estimated that each person carries about 100 new loss-of-function mutations. How does this number compare with your estimate of the number of mutations based on the mutation rate? What might account for any differences?

Q: Which type of mutation is simulated in the following example?   Wild type: THE ONE BIG FLY HAD…

A: The mutation simulated is point mutation.

Q: Which type of mutation best describes a change in a non-coding region of the genome?

A: Mutation: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to…

Q: frequency or decrease in frequency over time? Mutation that is harmful: Mutation that is…

A: Answer Mutation is a change in nucleotide sequence which results in different phenotype.  If…

Q: 2. Imagine a combination of microevolutionary mechanisms other than mutation/se- lection. How do you…

A: Microevolution is characterized as the adjustment of the allele frequencies over the long haul in a…

Q: Explain why harmful mutations tend to disappear, while beneficial mutations become widespread.

A: Mutation can be defined as a heritable genetic change in the genetic material of an organism that…

Q: What is a mutation? How does a mutation lead to an altered phenotype? Describe two specific types of…

A: The cell is the basic structural and functional unit of the body. A cell is composed of various cell…

Q: Leber congenital amaurosis (LCA) is a form  of congenital blindness in humans and is  known to be…

A: Leber congenital amaurosis (LCA) is a form of congenital blindness in humans and is known to be…

Q: A gene has length of 10000 nucleotides, some of them are ancestral (A) and others are mutant letters…

A: Assume M(t) represents the quantity of modified nucleotides at generation t and number of ancestors'…

Q: You have sequenced a few individuals in the population and found out that there are only two alleles…

A: Mutation is defined as the change in sequence of a gene in the DNA.

Q: What factors influence the mutation rates of human genes?

A: Changes in Genetic material is called Mutation. It may be due to environmental processes or…

Q: Consider a bacterium that can synthesize an imaginary amino acid called fictamine. Initially,…

A: ANSWER;-  i) Gene Y codes for enzyme 1 because when gene Y is mutated, the activity of enzyme 1 is…

Q: Name three factors that can influence the mutation rates of human genes.

A: Mutation :  It is defined as a change in a DNA ( Deoxyribonucleic acid) sequence because of the…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: After isolating six Neurospora mutations, you mate A and a representatives of each in all pairwise…

A: We can determine that there are at least 4 different genes represented in this experiment, with the…

Q: Pierce and his wife Shirley have a daughter named Annie. When Annie is 15 years old, Pierce develops…

A: STEP 1. Genetic disorders are the disorders that are inherited from parents to progeny by the means…

Q: One unexpected result of the sequencing of the human genome was the finding that mutations in a…

A: The genetic information of all living organisms (except some viruses) is stored in the cell in the…

Q: What types of mutations occur (i.e. describe base substitution vs. frameshift, silent, missense, and…

A: A mutation is a permanent change in the sequence of DNA, which occurs during the recombination or…

Q: Are mutations equally likely to occur in all locations in the genome? Why or why not?

A: Mutation: The changes that occur in DNA sequence or helical structure due to mutagens. These are…

Q: What happens to the neuronal cell if the Na+-K+ ATPase pump is damaged?

A: The nervous system is one of the vital systems of a body. It is a system of nerves which carry…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.