Figure 16.5 In E. coli, the tip operon is on by default, while the lac operon is off. Why do you think that this is the case? In the absence of lactose, the lac repressor binds the operator, and transcription is blocked.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Figure 16.5 In E. coli, the tip operon is on by
default, while the lac operon is off. Why do you
think that this is the case?
In the absence of lactose, the lac repressor
binds the operator, and transcriptor is
blocked.
Promoter Operator lacz lacY lacA
Repressor
RNA Polymerase
In the presence of lactose, the lac repressor
is released from the operator, and
transcription proceeds at a slow rate.
Promoter Operator lacz lacY lacA
RNA Polymerase
Repressor
Lactose
CAMP-CAP complex stimulates PNA
Polymerase activity and increases PA
CAMP + Promoter Operator lacz lacy lacA
CAP
RNA Polymerase
CAMP
CAP
RNA Polymerase
However, even in the present of
CAMP-CAP complex, PNA symhesis is
blacked when reprehared to
the operator
Promoter Operator lacz lacy lacA
Repressor
Figure 16.5 Regulation of the lac operon. Transcription of the lac operon is carefully regulated so that its
expression only occurs when glucose is limited and lactose is present to serve as an alternative fuel source.
Transcribed Image Text:Figure 16.5 In E. coli, the tip operon is on by default, while the lac operon is off. Why do you think that this is the case? In the absence of lactose, the lac repressor binds the operator, and transcriptor is blocked. Promoter Operator lacz lacY lacA Repressor RNA Polymerase In the presence of lactose, the lac repressor is released from the operator, and transcription proceeds at a slow rate. Promoter Operator lacz lacY lacA RNA Polymerase Repressor Lactose CAMP-CAP complex stimulates PNA Polymerase activity and increases PA CAMP + Promoter Operator lacz lacy lacA CAP RNA Polymerase CAMP CAP RNA Polymerase However, even in the present of CAMP-CAP complex, PNA symhesis is blacked when reprehared to the operator Promoter Operator lacz lacy lacA Repressor Figure 16.5 Regulation of the lac operon. Transcription of the lac operon is carefully regulated so that its expression only occurs when glucose is limited and lactose is present to serve as an alternative fuel source.
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