Epithelial surfaces provide the first line of defense against infection by the use of several types of mechanisms. One of the chemical mechanisms used by epithelia is: Joining of epithelial cells by tight junctions Secretion of antimicrobial peptides by epithelial cells Production of mucus, tears, or saliva in the nose, eyes, and oral cavity Movement of mucus by cilia Peristalsis in the gastrointestinal tract

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