Identify if the statement is True or False. If the statement is false, identify what is incorrect and correct it.  Cellular response to injury depends on nature, duration and severity of injury and Consequences of injury depend on type, state and adaptability of the injured cell. The causes of cellular injury can be a depletion of ATP, mitochondrial Damage, and entry of Calcium into the cell, increase reactive oxygen species (ROS), membrane Damage, DNA damage and Protein misfolding.  Intracellular Ca++ is normally low and is sequestered in mitochondria and endoplasmic reticulum. Increased cytosolic Ca++ activates enzymes such as ATPase, phospholipases, proteases, endonucleases that can lead to cell injury and death.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Identify if the statement is True or False. If the statement is false, identify what is incorrect and correct it. 

Cellular response to injury depends on nature, duration and severity of injury and
Consequences of injury depend on type, state and adaptability of the injured cell.

The causes of cellular injury can be a depletion of ATP, mitochondrial Damage, and
entry of Calcium into the cell, increase reactive oxygen species (ROS), membrane
Damage, DNA damage and Protein misfolding. 

Intracellular Ca++ is normally low and is sequestered in mitochondria and
endoplasmic reticulum. Increased cytosolic Ca++ activates enzymes such as
ATPase, phospholipases, proteases, endonucleases that can lead to cell injury and
death.

 

 

 

 

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