14. One of the subunits of the human telomerase is coded by the gene TERT. What would be aconsequence of a non-synonymous mutation in TERT that would make the telomerase non-functional?A. The shortening of chromosomes over successive generationsB. The addition of TTAGGG at the telomeresC. The lengthening of chromosomes over successive rounds of replicationD. The synthesis of a single, long and continuous Okazaki fragmentE. The inhibition of translation

Telomeres are protective structures located at the ends of chromosomes that play a crucial role in…

e subunits of the human telomerase is coded by the gene TERT. What wou of a non-synonymous mutation in TERT that would make the telomerase hortening of chromosomes over successive generations ddition of TTAGGG at the telomeres engthening of chromosomes over successive rounds of replication ynthesis of a single, long and continuous Okazaki fragment nhibition of translation

e subunits of the human telomerase is coded by the gene TERT. What wou of a non-synonymous mutation in TERT that would make the telomerase hortening of chromosomes over successive generations ddition of TTAGGG at the telomeres engthening of chromosomes over successive rounds of replication ynthesis of a single, long and continuous Okazaki fragment nhibition of translation

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter18: Dna Technologies: Making And Using Genetically Altered Organisms, And Other Applications

Section: Chapter Questions

Problem 12TYK: Discuss Concepts A forensic scientist obtained a small DNA sample from a crime scene. In order to...

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Q.Sheltrin protein complex that has the following function: a.Protect telomerase from damage b.Protect telomere from damage c.Proteins as chaperones in autophagy d.Responsible in Proteostasis Q.Telomeres shorten by 50-200 bases with every cell division due to. a.End replication problem b.Cellular senescence c.mutations of Sheltrin proteins d.DNA Recombination
3b) Briefly explain what telomerase does, how it accomplishes what it does, and why that allows a cell to completely and accurately replicate the ends of linear DNA molecules. (please note that the question does not ask you to explain the entire process of replication of the end of a linear DNA strand, it only asks about the function of telomerase in this process)
a. What DNA sequences are found at the telomeresof human chromosomes?b. What functions do the two telomere-associatedcomplexes, telomerase and shelterin, fulfill at chromosome ends?c. Where do you think that the RNA component oftelomerase comes from?
9. Answer BOTH parts of this question. Give an appraisal of prokaryote cell lines as recombinant polypeptide expression systems. (a) Evaluate the benefits and hindrances associated with protein PEGylation. (b)
1. Describe the process of autophosphorlyation 2. Differentiate between chromosomes and genes. 3. Think about what happens at the replication fork. If the gene for helicase is mutated, what part of replication will be affected and how? 4. There are three common types of chemical changes that can damage DNA at any time post-replicatively. In basic terms, name and describe any two of the three types of damage. please help me quick
23. What process best describes the action of Taq DNA polymerase? a. Catalyzes hydrolysis of phosphodiester bond b. Catalyzes an oxidation-reduction reaction c. Catalyzes the formation of a phosphodiester bond
1. In animals, cytokinesis occurs in which of the following phases of mitosis? a. Telophase b. Interphase c. Anaphase d. Prophase 2. Which of the following best describes the function of telomerase? a. The telomerase uses its RNA component as a template and performs reverse transcription to extend the telomeres. b. The telomerase uses an external RNA transcript as a template and performs reverse transcription to extend the telomeres. c. The telomerase uses its RNA component as a template and recruits DNA polymerase I to extend the telomeres. d. The telomerase uses an external RNA transcript as a template and recruits DNA polymerase I to extend the telomeres. 3. Which of the following is not involved in the elongation of prokaryotic peptide? a. EE-Tus, EE-Ts, EF-G factors b. mRNA c. peptidyl transferase d. formyl met tRNA
A mutant DNA strand was transcribed then translated to proteins. a. What is the protein product of the mutant DNA strand? The sequence of the mutant strand is shown below: 5'-TGCCATAACTGTTCGTACTGGCAAATTGCC-3' 3'-ACGGTATTGACAAGCATGACCGTTTAACGG-5' b. The mutation altered the sequence of the wild type template DNA such that a degenerate codon for a basic amino acid in the wild type was converted to a non-degenerate codon resulting in the sequence for the mutant strand shown. What was the original amino acid? c. Compare the charges and pl of the mutant peptide and the normal (wild- type) peptide at physiological pH?
Discuss Concepts A forensic scientist obtained a small DNA sample from a crime scene. In order to examine the sample, he increased its quantity by cycling the sample through the polymerase chain reaction. He estimated that there were 50,000 copies of the DNA in his original sample. Derive a simple formula and calculate the number of copies he will have after15 cycles of the PCR.
A binding .site for RNA polymerase is called a ___ . a. gene b. promoter c. codon d. protein
A scientist creates fruit fly larvae with a mutation that eliminates the exonuclease function of DNA pol III. Which prediction about the mutational load in the adult fruit flies is most likely to be correct? The adults with the DNA pol III mutation will have significantly more mutations than average The adults with the DNA pol III mutation will have slightly more mutations than average The adults with the DNA pol III mutation will have the same number of mutations as average The adults with the DNA pol III mutation will have fewer mutations than average.
Please consider figures 1 and 2 below. 5' A B 5' -I H. D. Figure 1: Replication Figure 2: Transcription a. Which letters, A to J represent DNA strands that will be synthesized continuously? b. At which letter, A to J, are ribonucleotides being added? c. Name and describe the process that occurs in prokaryotes as the synthesized mRNA hangs free of the double helix while transcription continues. d. In what direction will the replication bubble move in figure 1 as replication continues? Rleace Ibol ancwors (a) to (d)