Answered: e following genetic and cellular…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Related questions

Question

The lac operon of E. coli controls the expression of genes that code for enzymes involved in lactose metabolism. Mutations to various regions of the lac operon have been discovered which affect both the control of gene expression and the function of the gene products. These mutations include:

I ^- = produces a repressor protein that cannot bind to the operator region

I^S = produces a repressor protein that cannot be removed from the operator region

O^C = cannot bind a repressor protein

Z ^- = produces a defective (non-functioning) β-galactosidase enzyme

+ = wild type

Detail the functionality of the lac operon under the following genetic and cellular conditions. You do not need to consider the role of CAP in your analysis.

Genes

Repressed (yes/no)

Constitutive (yes/no)

I^S O⁺ Z⁺

I^S O^C Z⁺

Expert Solution

Step 1

Upper operon - I^sis super repressor. Once it is present in the sequence, it can not be removed. If it is not removed from the operator, RNA Polymerase can't bind to it so no transcription occurs. It remains repressed.