Draw the major product formed for each reaction. Assume the reactions are irreversible. Include stereochemistry when products contain stereocenter(s). It may be helpful to first identify whether the reaction is a substitution (and SN1 or SN2), an elimination (and E1 or E2) or a carbonyl addition. (a) 1 equiv means for every molecule of substrate, there is one molecule of NaOCH3 Br Br NaOCH 3 (1 equiv) 0 °C (b) Draw only the substitution product. Both elimination and substitution occur here. (၁) CH3 Br Br CH3OH NaOCH3 80 °C (d) "Then" means CHзl is added after the Grignard reacts. H3C MgBr (1 equiv) then CH3l

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter11: Reactions Of Alkyl Halides: Nucleophilic Substitutions And Eliminations
Section11.SE: Something Extra
Problem 53AP
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Draw the major product formed for each reaction. Assume the reactions are irreversible.
Include stereochemistry when products contain stereocenter(s). It may be helpful to first
identify whether the reaction is a substitution (and SN1 or SN2), an elimination (and E1 or E2)
or a carbonyl addition.
(a) 1 equiv means for every molecule of substrate, there is one molecule of NaOCH3
Br
Br
NaOCH 3 (1 equiv)
0 °C
(b) Draw only the substitution product. Both elimination and substitution occur here.
(၁)
CH3
Br
Br
CH3OH
NaOCH3
80 °C
(d) "Then" means CHзl is added after the Grignard reacts.
H3C
MgBr
(1 equiv)
then CH3l
Transcribed Image Text:Draw the major product formed for each reaction. Assume the reactions are irreversible. Include stereochemistry when products contain stereocenter(s). It may be helpful to first identify whether the reaction is a substitution (and SN1 or SN2), an elimination (and E1 or E2) or a carbonyl addition. (a) 1 equiv means for every molecule of substrate, there is one molecule of NaOCH3 Br Br NaOCH 3 (1 equiv) 0 °C (b) Draw only the substitution product. Both elimination and substitution occur here. (၁) CH3 Br Br CH3OH NaOCH3 80 °C (d) "Then" means CHзl is added after the Grignard reacts. H3C MgBr (1 equiv) then CH3l
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