Diagramming Cell Communication Remember: SHAPE DETERMINES FUNCTION Insulin is a hormone that is produced by the pancreas. It circulates around the body in the blood and binds to receptor proteins in the cell membrane of cells to "unlock" them and allow sugar to enter the cell. In people with type 2 diabetes, the shape of the receptor protein in the cell membranes is changed due to poor diet. As a result, insulin is no longer the correct shape to bind, and sugar stays in the blood.   For this assignment, I would like you to make two drawings: Show insulin correctly binding to a receptor protein in a normal person's cell membrane. Show insulin UNABLE to bind to a receptor protein in the cell membrane of a person with Type 2 diabetes. The receptor should be an INCORRECT SHAPE to match the insulin molecule.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section4.5: Intercellular Communication And Signal Transduction
Problem 3CYU: Outline the three general means by which binding of a water soluble extracellular chemical messenger...
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Diagramming Cell Communication

Remember: SHAPE DETERMINES FUNCTION

Insulin is a hormone that is produced by the pancreas. It circulates around the body in the blood and binds to receptor proteins in the cell membrane of cells to "unlock" them and allow sugar to enter the cell.

In people with type 2 diabetes, the shape of the receptor protein in the cell membranes is changed due to poor diet. As a result, insulin is no longer the correct shape to bind, and sugar stays in the blood.

 

For this assignment, I would like you to make two drawings:

  1. Show insulin correctly binding to a receptor protein in a normal person's cell membrane.
  2. Show insulin UNABLE to bind to a receptor protein in the cell membrane of a person with Type 2 diabetes. The receptor should be an INCORRECT SHAPE to match the insulin molecule.

 

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