Consider the function of the cofactor FAD. Which of the following makes it unique (different) from NAD+? Select all that apply. O Operates as part of an enzyme and is not a mobile electron carrier O In its fully reduced state, carries 2 electrons O Involved in electron transfers as part of pyruvate dehydrogenase complex activity Facilitates single electron transfers

Consider the function of the cofactor FAD. Which of the following makes it unique (different) from NAD+? Select all that apply. O Operates as part of an enzyme and is not a mobile electron carrier O In its fully reduced state, carries 2 electrons O Involved in electron transfers as part of pyruvate dehydrogenase complex activity Facilitates single electron transfers

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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The image below shows part of a key catabolic pathway. If an individual had a deficiency for the enzyme required at point "X", would they still be able to produce a high rate of ATP during very strenuous exercise? ATP in Glucose Prep. phase Payoff phase ļ - MacRoc Pyruvate →→→ Anaerobic fate of pyruvate ATP out ▬OD OF 1- HP 01 -- Select one: O a. No, because NAD* will not be regenerated by lactate dehydrogenase. The reduction of NAD+ to NADH is a required step during the payoff phase of glycolysis. O b. No, because lactate dehydrogenase is required for the continued recycling of NAD+ to NADH, thus allowing glycolysis to continue. Oc. Yes, because pyruvate dehydrogenase is necessary to produce acetyl-CoA, which under these conditions will feed into the citric acid cycle. Od. Yes, because this enzyme is responsible for the substrate-level phosphorylation necessary to maintain the ATP input for the preparatory phase of glycolysis. DE Report question issue Notes + 14:12 ( CE
Concerning the citric acid cycle (TCA cycle), which of the following statements is false? The TCA cycle generates electron carriers Oxidation of pyruvate in the matrix of the mitochondria produces sixteen total electrons Substrate level phosphorylation in the TCA cycle produces 2 GTP per the oxidation of a single glucose molecule The fate of the carbonyl carbon of acetyl CoAin the TCA cycle is to be lost as CO2 in the second turn Oxygen is required to regenerate electron acceptors
Cancer cells need more DNA synthesis but the NADPH/ NADP* ratio is high. Which of the following statement is TRUE? Flux through the oxidative reactions is low and the nonoxidative reactions are reversed in order to form ribose 5-phosphate. O b. The oxidative reactions and the isomerase supply both ribose 5-phosphate and NADPH with little flux through the nonoxidative branch. O C. Flux through the oxidative reactions increases and ribose 5-phosphate is shunted into glycolysis by the nonoxidative reactions. Od. The ribose 5-phosphate is recycled through the oxidative steps via the nonoxidative reactions and gluconeogenesis.
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Tell how many ATPs result from from oxidative phosphorylation of one NADH; tell how many ATPs result from oxidation phosphorylation of one FADH2.
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A cell is grown on minimal media containing only 3-phosphoglyceric acid as a source of carbon and energy. What is the most likely place this compound would enter the metabolic cycle? O Glycolysis O Conversion of Pyruvate to Acetyl-CoA O The TCA Cycle The Electron Transport Chain
Which of the following conditions must be met within the cell In order for the enzyme pyruvate carboxylase to be activated? Select all that apply. NADP+ levels must be high Phosphofructokinase must be in the activated R-state Beta-oxidation of fatty acids happening in the mitochondrial matrix AMP levels must be high ATP levels must be high
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Organisms growing anaerobically cannot perform glycolysis for long without reducing the pyruvate from glycolysis into another compound, most commonly to lactate or to ethanol plus CO2. Which of the following provides the best explanation for sustaining anaerobic glycolysis? O Lactic acid has to be reduced to regenerate NADH Pyruvate has to be reduced to regenerate NADH Pyruvate has to be reduced to regenerate NAD+ Lactic acid has to be reduced to regenerate NAD+
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