If a cell is fed a large supply of fatty acids, which outcome can be expected? Glycolysis will be stimulated and pyruvate oxidation will be inhibited as acetyl CoA builds up to high levels in the cell. Glycolysis and pyruvate oxidation will be stimulated, causing citrate to build up and activate fatty acid synthase. Oxidation of fatty acids to form acetyl CoA will be stimulated, which will stimulate gluconeogenesis to form glucose that the cell can store as an energy resource. Oxidation of fatty acids through the citric acid cycle will be stimulated until ATP builds up and inhibits citrate synthase, diverting fatty acids into storage molecules such as triglycerides. The excess fatty acids will deplete the oxygen supply, causing everything except glycolysis to shut down and activating the lactic acid fermentation pathway.

If a cell is fed a large supply of fatty acids, which outcome can be expected? Glycolysis will be stimulated and pyruvate oxidation will be inhibited as acetyl CoA builds up to high levels in the cell. Glycolysis and pyruvate oxidation will be stimulated, causing citrate to build up and activate fatty acid synthase. Oxidation of fatty acids to form acetyl CoA will be stimulated, which will stimulate gluconeogenesis to form glucose that the cell can store as an energy resource. Oxidation of fatty acids through the citric acid cycle will be stimulated until ATP builds up and inhibits citrate synthase, diverting fatty acids into storage molecules such as triglycerides. The excess fatty acids will deplete the oxygen supply, causing everything except glycolysis to shut down and activating the lactic acid fermentation pathway.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 21P: Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and...

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