Can you explain why when the pH level was changed from 0 to 5, the ATP production was affected despite the supply of glucose being constant at just 1 mol for both treatments (At 0 pH and 5 pH). What is the reason on why this could have happened? ATP Graph1005.003710Relative Percent Oxygen0 2550 7575 100pH of intermembrane space0 3.5 7 10.5 1400initial NADH (mol)10 20 30 40ITemperature (°C)20 40 60 8080 100initial Glucose (mol)0 2 4 6 8 10IIinitial ATP (mol)0 20 40 60 80 100IIDNPI?IIMetabolism of 1 Mole of Glucose ATP Production Oxygen Consumption NADH ProductionATP ProductionATP Concentration (moles)3002251507524610Milliseconds-Run 1 -- Run 28121416Potential (mV)1820

ATP synthesis can occur by 2 modes: Substrate level phosphorylation Oxidative phosphorylation…

Can you explain why when the pH level was changed from 0 to 5, the ATP production was affected despite the supply of glucose being constant at just 1 mol for both treatments (At 0 pH and 5 pH). What is the reason on why this could have happened?

Can you explain why when the pH level was changed from 0 to 5, the ATP production was affected despite the supply of glucose being constant at just 1 mol for both treatments (At 0 pH and 5 pH). What is the reason on why this could have happened?

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Related questions

Q: How many ATPs are there in this triglyceride? Showing NADH and FADH2 calculations and steps

A: Triglycerides broken down into glycerol and three fatty acids containing 12, 16 and 14 carbon atom…

Q: provide a solution using a table, listing all the specific individual reactions that will generate…

Q: Kinases catalyze the transfer of which group from one molecule to another? A) carboxyl group b)…

A: Enzymes are also extremely specific, which means they can only catalyze particular reactions,…

Q: An enzyme is found that catalyzes the reaction: A B A researcher have determined KM and kcat to be 4…

A: Concentration can be expressed in various units like Molar(M) , millimolar (mM) , micromolar (μM) ,…

Q: Carboxylic acids do not readily undergo certain biochemical reactions; thus, they are often…

A: Carboxylic acids contain a carbonyl carbon attached to hydroxyl group. This arrangement facilitates…

Q: Incubating 10µl of an LDH sample for 5 min in the presence of 60mM of lactate and 100mM NAD+…

A: Lactate Dehydrogenase (LDH) activity can be figured using a spectrophotometric assay. The reaction…

Q: You are trying to come up with a drug to inhibit the activity of an enzyme thought to have a role…

A: Km (also known as Michaelis constant) is the substrate concentration that allows the enzyme to gain…

Q: The following scheme shows how acetylcholine esterase (AChE) enzyme hydrolyzes acetylcholine (ACh).…

A: A cholinergic enzyme called acetylcholinesterase (AChE) is mainly present in postsynaptic…

Q: 17 Refer to the table. Reaction Chemical equation (kcal/mol) 2 glucose → maltose + H₂O +4.0…

A: The chemical reactions take place with the change of energy. The spontaneous reactions release…

Q: Calculate AG for ATP hydrolysis in muscle at 16 °C. Use the muscle concentrations from the first…

A: Standards free energy change calculated at biochemical standards is called biochemical standard free…

Q: The phosphoanhydride bond that links two phosphate groups in ATP in a high-energy linkage has a ΔG°…

A: ATP is the primary source of energy of the cell. ATP is made up of an adenosine bound to three…

Q: an enzyme acts on a substrate X. The enzyme exists in four different forms, with different catalytic…

A: Enzymes are proteins that can act as biocatalysts. Substrates bind to the active site of the enzyme,…

Q: An allosteric enzyme that follows the concerted mechanism has a T/R ratio of 500 in the absence of…

A: Enzymes are a type of catalyst that is responsible for enabling and accelerating many important…

Q: Please answer both parts A.Phosphate-containing compounds, such as ATP, are considered “high-energy”…

A: ATP is the energy currency of the living cells. It is a link between anabolism and catabolism. ATP…

Q: Knowing that there is usually an optimum pH for enzyme activity, what do you think would happen if…

A: The pH scale is used to measure the acidity or alkalinity of a molecule and change in pH of a…

Q: - wide is a toxic chemical that hinders the production of ATP by inhibiting the enzyme cytochrome…

A: Cyanide is an inhibitor which inhibits the oxidative phosphorylation process where it inhibits…

Q: Plotting Reaction Progression: In each case make reasonable, relative, plots of every reees every…

A: Limiting reactant in the reaction is reactant that determines how much of the products are made.

Q: Phosphorylated compounds with a high hydrolysis rate have a high phosphoryl group transfer…

A: Phosphoryl group transfer potential is simply a measure of the ability of a phosphorylated group to…

Q: C12. A biochemical reaction, X à Y, has an equilibrium constant of 2500 in the presence of an enzyme…

A: in above question Equilibrium constant given is 2500 Enzymes- biological catalyst Enzymes helps…

Q: In order to maintain optimal enzyme efficiency, the pH of human blood must be approximately 7.39.…

A: Enzymes are proteins that aid in the speeding up of metabolism, or the chemical events that occur in…

Q: Enzyme X exhibits maximum activity at pH = 6.3. X shows a fairly sharp decrease in its activity when…

A: Enzymes are high molecular-weight protein molecules that catalyse biochemical reactions. The…

Q: Which two enzyme curves would be generated from a themophilic bacteria that lives in a strongly acid…

A: Thermophilic bacteria are extremophiles who survive at high temperature ranges (above 40 degrees…

Q: In muscle cells, the AG for glucose+ATP = glucose– 6–P+ADP is –33.5 kJ·mol-1. In contrast, the AG…

A: During glycolysis, Glucose is converted into Pyruvate. The first step of glycolysis is the…

Q: In an experiment to test the activity of lactase under different conditions, tubes containing…

A: Lactase, a sugar found in milk, is a digestive enzyme that catalyzes the breakdown of lactose.…

Q: Briefly explain Boyer’s binding change mechanism for the ATP synthase.

A: ATP synthase is an enzyme present in the inner mitochondrial membrane which catalyzes the reversible…

Q: Suppose you have 100 molecules of an enzyme (an aspartyl protease) that requires aspartate in the…

A: Pka of aminoacid is important to know the pH at which the Amino acid is protonated or deprotonated.…

Q: The hexokinase can be inhibited by a non competitive inhibitor. On your enzyme show where the non…

A: Hexokinase catalyzes the reaction of glucose binding to ATP to form glucose 6 phosphate. The…

Q: Many types of cells are able to use membrane-spanning transport proteins and a source of energy to…

A: a) Given reaction is: Glc(out) + ATP+H2O ↔Glc(in) + ADP + PiEquilibrium constant is the expression…

Q: An enzyme active site contains a lysine that acts as through electrostatic catalysis (proximity and…

A: Hi! Thank you for the question. As you have posted a question with multiple subparts, I will be…

Q: In contrast to phospholipids, the transport of fatty acids across membranes is much more rapid (less…

A: Phospholipids are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate…

Q: ou know that the free energy of ATP hydrolysis depends on the ATP/ADP ratio. Given that under…

A: ATP is the energy currency of the cell.

Q: Calculate the amount of ATP that be needed to be converted to ASP to pump 1mol of protons across a…

A: Introduction The free energy available from the movement of protons is given by…

Q: Please provide a supportive statement about why you picked each of the two curves you picked. Your…

A: Thermophilic bacteria are those bacteria that can live in a High temperature environment. Like…

Q: The reactions A B and X Y are started under standard biochemical conditions. They are fast and…

A: Explanation: This can be explained using the reaction isotherm equation, as shown below

Q: Why is understanding reaction rates significant? Indicate at least 3 key importance of understanding…

A: Enzymes are biocatalyst that increases the speed of reaction by lowering the activation…

Q: The blue structure in the diagram below is an enzyme. Please discuss what these diagrams (A and B)…

A: Enzyme is used to carry a reaction where a substrate is converted into a product. The molecule that…

Q: Suppose that you measure the pH-dependence of an enzymatic reaction and you see a bell-shaped curve.…

A: Enzymes are specialized proteins that catalyze all biochemical reactions. Enzymes are categorized…

Q: A researcher investigates the effect of eight different pH levels on the reactions catalyzed by the…

A: Enzymes are proteins which function as biological catalysts to help regulate chemical reactions.…

Q: Calculate your dilution strategyto make a 625 ng/mLHRP solution from a 12.5 μg/mL stock given the…

A: Final solution that has to be prepared: 625 ng/mL of HRP solution. Stock solution given: 12.5 μg/mL…

Q: The following data were collected in the study of a new enzyme and an inhibitor of the new enzyme:

A: The Michaelis–Menten equation is the rate equation for a one-substrate enzyme-catalyzed reaction.…

Q: When the rate of reaction decreases, what is happening to the enzyme, catalase? Did your actual…

A: Enzymes have the ability to lower the activation energy of a chemical reaction by interacting with…

Q: Free energy changes under intracellular conditions differ markedly from those determined under…

A: ATP (Adenosine triphosphate) hydrolysis is a reaction process in which the high energy stored in the…

Question

ATP Graph
100
5.0
0
37
1
0
Relative Percent Oxygen
0 25
50 75
75 100
pH of intermembrane space
0 3.5 7 10.5 14
0
0
initial NADH (mol)
10 20 30 40
I
Temperature (°C)
20 40 60 80
80 100
initial Glucose (mol)
0 2 4 6 8 10
I
I
initial ATP (mol)
0 20 40 60 80 100
I
I
DNP
I
?
I
I
Metabolism of 1 Mole of Glucose ATP Production Oxygen Consumption NADH Production
ATP Production
ATP Concentration (moles)
300
225
150
75
2
4
6
10
Milliseconds
-Run 1 -- Run 2
8
12
14
16
Potential (mV)
18
20

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: ATP synthesis

VIEW

Step 2: Effect of pH on oxidation phosphorylation

VIEW

Solution

VIEW

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Similar questions

Human lysozyme is an enzyme active in lysosomes. At approximately what pH would you expect this enzyme to display maximal activity? Question options: enzyme activity should be reasonably similar at all of these pH values 9 7 5 11
Can you please solve the following question, both parts please.
A particular reaction has a ΔG‡ of 37.0 kJ mol-1. In the presence of an enzyme, the same reaction has a ΔG‡ of 5.70 kJ mol-1. Calculate the value of ΔΔG‡ in kJ mol-1.
In vivo, ATP is usually bound to magnesium or manganese ions. Why is this the case?
V-class proton pumps run backward relative to the F-class ATP synthase. Consider the cartoon, which shows the conformations of the beta-subunits and ATPIADP + Pj of the F-class synthase. Which of the following associations between the conformation of the beta subunit and ATP/ADP + P¡ is correct for V- Binding Change Mechanism loose binding ADP+P ATP ATP class pumps? C repeat ADP + P, ADP АТР tight binding АТР +P оpen АТР O The open conformation releases ATP. Hydrolysis of ATP to ADP + P¡ drives the change from tight to loose. O Binding of ADP + P¡ drives change from open to loose. Hydrolysis of ATP to ADP + Pj drives the change from open to loose.
Can you explain the answe?
I need the answer as soon as possible
DNA, which is negatively charged, can adsorb onto the surface of citrate-capped Au nanoparticles. Explain why such a system would exhibit a Langmuir adsorption isotherm.
8
Give detailed Solution with explanation (no need Handwritten answer
When reviewing a Michaelis-Menten Saturation Curve, at first the rate of the reaction is relatively constant, but the rate decreases as the substrate is used up and eventually reaches a plateau. Afte reaching this plateau, what would speed up the reaction again? Adding more substrate Adding heat Adding more enzyme Adding cofactors
The covalent catalytic mechanism of an enzyme depends on a single active site Cys whose pK is 8. A mutation in a nearby residue alters the micro environment so that this pK increases to 10. Would the mutation cause the reaction rate to increase or decrease? Explain.