Calcium channel blockers are drugs used to treat people with high blood pressure. They mostly affect the smooth muscle in blood vessels. Why would blockage of calcium channels in these cells lead to a decrease in blood pressure. These drugs also can affect the myocardial muscle of the hear, where they decrease the strength of myocardial contraction. Explain why they have this effect. In some people, these drugs have a side effect of decreasing intestinal motility, but are not likely to have side effects of decreasing skeletal muscle contraction. Yet muscles in both places require calcium. Explain why side effects are more likely in intestine than in skeletal muscle.
Musculoskeletal System
The musculoskeletal system, also called the locomotor system, is an organ system that gives humans and animals the ability to move using their muscular and skeletal systems. It provides stability, form, support, and movement to the body. The skeleton is composed of bones (skeleton), muscles, cartilage, tendons, ligaments, joints, and other connective tissue that supports and binds tissues and organs together. The musculoskeletal system is subdivided into two broad systems, such as the muscular system and the skeletal system.
Skeletal structure
The skeletal system is the core framework of the human body. The skeletal structure comprises bones and connective tissue, including cartilage, ligaments, and tendons. The skeletal structure of our body acts as a support structure. It maintains the body's shape and is responsible for its movement, blood cell formation, protection of organs, and mineral storage. The skeletal system is referred to as the musculoskeletal system.
- Calcium channel blockers are drugs used to treat people with high blood pressure.
- They mostly affect the smooth muscle in blood vessels. Why would blockage of calcium channels in these cells lead to a decrease in blood pressure.
- These drugs also can affect the myocardial muscle of the hear, where they decrease the strength of myocardial contraction. Explain why they have this effect.
- In some people, these drugs have a side effect of decreasing intestinal motility, but are not likely to have side effects of decreasing skeletal muscle contraction. Yet muscles in both places require calcium. Explain why side effects are more likely in intestine than in skeletal muscle.
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