Briefly explain the role of genetic testing and the following inherited gene mutations linked to breast cancer: ATM BRCA1andBRCA2 BRIP 1 CDH1 CHEK2 PALB2 PTEN STK11 TP53

Q: D. What is the best term for a normal INK gene? (tumor suppressor) (inactive tumor suppressor)…

A: Tumor-suppressor genes are those genes which do not allow the cell to grow rapidly and in an…

Q: 1 at birth 1 2 This pedigree illustrates the occurrence of neurofibromatosis in a small human family…

A: A pedigree is a chart that delineates the hereditary ties and patterns of inheritance between…

Q: Part 3C: Below is data from a pedigree trace of patients affected with mouse model of pancreatic…

A: Answer  The mode of inheritance shown in the above pedigree is of autosomal recessive

Q: manifestations in the event that the BRCA1 tumor suppressor gene accumulates mutations.

A: the cancer cell produces abnormal protein and their uncontrolled growth will lead to formation of…

Q: What significance do BRCA1 and BRCA2 have in regard to developing cancer, and what types of cancer…

A: BRCA 1 & BRCA 2 are found pair in all the organisms where one gene is obtained from each of the…

Q: Which of the following mutations is likely to be associated with development of cancer? Loss of SMO…

A: The cells are basic structural and functional units of life. The human body contains many types of…

Q: The mutation of which of the following proto-oncogenes can lead to an increased susceptability to…

A: Introduction:- Cancer or malignancy is defined as the uncontrolled and unregulated proliferation of…

Q: Mrs. Ortez has type III breast cancer and is now concluding the trial portion of a certain research…

A: Stage III breast cancer is a stage where the cancer has spread beyonf the tumor region and might…

Q: Answer the following multiple-choice questions about cancer-promoting mutations. A gene whose…

A: Cancer cells by definition, proliferate in defiance of normal controls and are able to invade and…

Q: Discuss how oncogenes and tumor suppressor genes are related to genes involved in the control of…

A: Tumor suppressor genes are the regular genes present in the genome which are important for the…

Q: Match the letter of the drug/treatment w Cell cycle inhibitor directed against breast cancer Gene…

A: Abnormal cell growth with the potential to invade or spread to other parts of the body is called…

Q: A 6-year old Caucasian girl from northern Europe, with a family history of melanoma, has recently…

A: Melanoma is a kind of cancer affecting the melanocytes (cells that control pigmentation of the…

Q: p53 is an important DNA damage checkpoint protein that stops the transition to S phase and is lost…

A: p53, also known as TP53 or tumor protein (EC :2.7. 1.37) is a gene that codes for a protein that…

Q: Which of the following is NOT an advantage of autologous embryonic stem cell development and…

A: Embryonic stem cells (ESCs) are pluripotent cells derived from embryos, and they are not considered…

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A: These are genes that inhibits cell division of the cell, repair mistakes in DNA or control apoptosis…

Q: Apply the Key terms to fill in the blanks to demonstrate knowledge of cancer development. Key terms:…

A: 1. Regulator  2. Mutated 3.cell cycle 4.unrepaired 5. Check points.

Q: Classify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, Bcl-2,…

A: Proto-oncogene is a normal gene which have many different functions in the cell, like providing…

Q: Of the following choices a loss of function mutation would most lukely contribute to cancer onset if…

A: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to external…

Q: Explain the normal regulation of proto-oncogenes and tumor suppressor genes that prevents cells from…

A: Oncogenes and tumour suppressor genes are two types of genes that relate cell cycle regulation to…

Q: Explain in general what is meant by a proto-oncogene and how they are involved in the formation of a…

A: Proto-oncogenes are a bunch of normal genes present in a cell. They have the necessary information…

Q: "In most differentiated tissues, daughter cells retain a memory of gene expression patterns that…

A: The expression of specific genes inside each cell type is what causes cells to differentiate into…