Boris Magasanik collected data on the amounts of the bases of RNA isolated from a number of sources, expressed relative to a value of 10 for adenine (B. Magasanik, in The Nucleic Acids: Chemistry and Biology, vol. 1, E. Chargaff and J. N. Davidson, Eds. New York: Academic Press, 1955). Amount Organism and tissue A G C U Rat liver nuclei 10 14.8 14.3 12.9 Rabbit liver nuclei 10 13.6 13.1 14.0 Cat brain 10 14.7 12.0 9.5 Carp muscle 10 21.0 19.0 11.0 Yeast 10 12.0 8.0 9.8 a. For each organism, compute the ratio of (A + G)/(U + C). b. How do these ratios compare with the (A + G)/(T + C) ratio found in DNA? Explain.
Nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Nucleic Acids
Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
Boris Magasanik collected data on the amounts of the bases of RNA
isolated from a number of sources, expressed relative to a value of 10
for adenine (B. Magasanik, in The
Biology, vol. 1, E. Chargaff and J. N. Davidson, Eds. New York:
Academic Press, 1955).
Amount
Organism and tissue A G C U
Rat liver nuclei 10 14.8 14.3 12.9
Rabbit liver nuclei 10 13.6 13.1 14.0
Cat brain 10 14.7 12.0 9.5
Carp muscle 10 21.0 19.0 11.0
Yeast 10 12.0 8.0 9.8
a. For each organism, compute the ratio of (A + G)/(U + C).
b. How do these ratios compare with the (A + G)/(T + C) ratio found in
DNA? Explain.
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