he lower limit of detection of an EBV assay is 25 copies/mL. All controls were as expected, and the sample internal control was positive, but there was no signal observed from the target viral sequence. What explains this phenomenon? What is the appropriate way to report these results?
he lower limit of detection of an EBV assay is 25 copies/mL. All controls were as expected, and the sample internal control was positive, but there was no signal observed from the target viral sequence. What explains this phenomenon? What is the appropriate way to report these results?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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he lower limit of detection of an EBV assay is 25 copies/mL. All controls were as expected, and the sample internal control was positive, but there was no signal observed from the target viral sequence. What explains this phenomenon? What is the appropriate way to report these results?
Expert Solution
Step 1 Introduction:
EBV assay is a common tool to measure the presence of the virus in clinical samples. The lower limit of detection (LOD) for this assay is 25 copies/mL. In this study, we report a case where the LOD was not met, but all other controls were as expected.
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