**Lac Operon and Its Mutations** The lac operon controls the inducible expression of genes involved in lactose utilization. Several naturally occurring mutations have been discovered that affect how the lac operon operates. Consider the following mutations: - **I^-** = a mutation in the repressor protein that cannot bind the operator - **I^s** = a mutation in the repressor protein that cannot be removed from the operator - **O^c** = a mutation in the operator that cannot bind the repressor Detail the functionality of the lac operon with the following genotypes and cellular conditions (Note if there is no superscript, there is no mutation). | Genotype | Lactose present | Repressed (yes/no) | Constitutive (yes/no) | Inducible (yes/no) | |----------|-----------------|--------------------|------------------------|---------------------| | I, O | No | Yes | No | No | | I, O | Yes | No | No | Yes | | I, O^c | No | No | Yes | No | | I, O^c | Yes | No | Yes | No | | I^s, O | No | Yes | Yes | No | | I^s, O | Yes | Yes | Yes | No | | I^-, O | No | No | Yes | No | | I^-, O | Yes | No | Yes | No | | I^s, O^c | No | No | No | Yes | | I^s, O^c | Yes | No | No | Yes |
**Lac Operon and Its Mutations** The lac operon controls the inducible expression of genes involved in lactose utilization. Several naturally occurring mutations have been discovered that affect how the lac operon operates. Consider the following mutations: - **I^-** = a mutation in the repressor protein that cannot bind the operator - **I^s** = a mutation in the repressor protein that cannot be removed from the operator - **O^c** = a mutation in the operator that cannot bind the repressor Detail the functionality of the lac operon with the following genotypes and cellular conditions (Note if there is no superscript, there is no mutation). | Genotype | Lactose present | Repressed (yes/no) | Constitutive (yes/no) | Inducible (yes/no) | |----------|-----------------|--------------------|------------------------|---------------------| | I, O | No | Yes | No | No | | I, O | Yes | No | No | Yes | | I, O^c | No | No | Yes | No | | I, O^c | Yes | No | Yes | No | | I^s, O | No | Yes | Yes | No | | I^s, O | Yes | Yes | Yes | No | | I^-, O | No | No | Yes | No | | I^-, O | Yes | No | Yes | No | | I^s, O^c | No | No | No | Yes | | I^s, O^c | Yes | No | No | Yes |
Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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Transcribed Image Text:**Lac Operon and Its Mutations**
The lac operon controls the inducible expression of genes involved in lactose utilization. Several naturally occurring mutations have been discovered that affect how the lac operon operates. Consider the following mutations:
- **I^-** = a mutation in the repressor protein that cannot bind the operator
- **I^s** = a mutation in the repressor protein that cannot be removed from the operator
- **O^c** = a mutation in the operator that cannot bind the repressor
Detail the functionality of the lac operon with the following genotypes and cellular conditions (Note if there is no superscript, there is no mutation).
| Genotype | Lactose present | Repressed (yes/no) | Constitutive (yes/no) | Inducible (yes/no) |
|----------|-----------------|--------------------|------------------------|---------------------|
| I, O | No | Yes | No | No |
| I, O | Yes | No | No | Yes |
| I, O^c | No | No | Yes | No |
| I, O^c | Yes | No | Yes | No |
| I^s, O | No | Yes | Yes | No |
| I^s, O | Yes | Yes | Yes | No |
| I^-, O | No | No | Yes | No |
| I^-, O | Yes | No | Yes | No |
| I^s, O^c | No | No | No | Yes |
| I^s, O^c | Yes | No | No | Yes |
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