Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
The substrate has been represented bound to the enzyme pocket. 20 Zn Part A: Part B: Substrate Part C: lle Val A Increasing V Arg 1451 (1)=0 Carboxypeptidase A A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibition E. Non-competitive inhibitor F. -1/KM Benzylsuccinic acid Propose the types of biochemical interactions by which benzylsuccinic acid interacts with the carboxypeptidase A active site. 1. Hydrogen bond II. Ionic bond III.Hydrophobic interactions (Choose from options G-L) Which of the shown Lineweaver-Burk plots would you expect observe when benzylsuccinic acid I used to inhibit Carboxypeptidase A enzymatic activity? (Choose from options N-R) Increasing [1] Benzylsuccinic acid (shown below) has been identified as an inhibitor of carboxypeptidase A. Based on your understanding of enzyme- inhibitor interactions, identify a likely mechanism of inhibition by benzylsuccinic acid. (Choose from options A-E) in-o CH3 1/S) O V.(min) 20 Zn + No inhibitor H₂N Products of peptidase reaction lle Val -1/KM Increasing (1) Arg IV max IASI m=0 Part C: 1/vo A Which of the shown Lineweaver-Burk plots would you expect enzymatic activity? (Choose from options N-R) B Increasing (1) 1/Vmax 1/[S] [1] = 0 A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibitior E. Non-competitive inhibitor F. G. I only H. Il only 1. Ill only J. II and III only K. I and II only L. I, II and III M. N. Graph A O. Graph B P. Graph C Q. Graph D R. None of the given graphs 04/1 -1/KM Increasing [1], (1=0 1/[S] C ( N

The substrate has been represented bound to the enzyme pocket. 20 Zn Part A: Part B: Substrate Part C: lle Val A Increasing V Arg 1451 (1)=0 Carboxypeptidase A A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibition E. Non-competitive inhibitor F. -1/KM Benzylsuccinic acid Propose the types of biochemical interactions by which benzylsuccinic acid interacts with the carboxypeptidase A active site. 1. Hydrogen bond II. Ionic bond III.Hydrophobic interactions (Choose from options G-L) Which of the shown Lineweaver-Burk plots would you expect observe when benzylsuccinic acid I used to inhibit Carboxypeptidase A enzymatic activity? (Choose from options N-R) Increasing [1] Benzylsuccinic acid (shown below) has been identified as an inhibitor of carboxypeptidase A. Based on your understanding of enzyme- inhibitor interactions, identify a likely mechanism of inhibition by benzylsuccinic acid. (Choose from options A-E) in-o CH3 1/S) O V.(min) 20 Zn + No inhibitor H₂N Products of peptidase reaction lle Val -1/KM Increasing (1) Arg IV max IASI m=0 Part C: 1/vo A Which of the shown Lineweaver-Burk plots would you expect enzymatic activity? (Choose from options N-R) B Increasing (1) 1/Vmax 1/[S] [1] = 0 A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibitior E. Non-competitive inhibitor F. G. I only H. Il only 1. Ill only J. II and III only K. I and II only L. I, II and III M. N. Graph A O. Graph B P. Graph C Q. Graph D R. None of the given graphs 04/1 -1/KM Increasing [1], (1=0 1/[S] C ( N

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
The substrate has been represented bound to the enzyme pocket. 20 Zn Part A: Part B: Substrate Part C: lle Val A Increasing V Arg 1451 (1)=0 Carboxypeptidase A A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibition E. Non-competitive inhibitor F. -1/KM Benzylsuccinic acid Propose the types of biochemical interactions by which benzylsuccinic acid interacts with the carboxypeptidase A active site. 1. Hydrogen bond II. Ionic bond III.Hydrophobic interactions (Choose from options G-L) Which of the shown Lineweaver-Burk plots would you expect observe when benzylsuccinic acid I used to inhibit Carboxypeptidase A enzymatic activity? (Choose from options N-R) Increasing [1] Benzylsuccinic acid (shown below) has been identified as an inhibitor of carboxypeptidase A. Based on your understanding of enzyme- inhibitor interactions, identify a likely mechanism of inhibition by benzylsuccinic acid. (Choose from options A-E) in-o CH3 1/S) O V.(min) 20 Zn + No inhibitor H₂N Products of peptidase reaction lle Val -1/KM Increasing (1) Arg IV max IASI m=0
Transcribed Image Text:The substrate has been represented bound to the enzyme pocket. 20 Zn Part A: Part B: Substrate Part C: lle Val A Increasing V Arg 1451 (1)=0 Carboxypeptidase A A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibition E. Non-competitive inhibitor F. -1/KM Benzylsuccinic acid Propose the types of biochemical interactions by which benzylsuccinic acid interacts with the carboxypeptidase A active site. 1. Hydrogen bond II. Ionic bond III.Hydrophobic interactions (Choose from options G-L) Which of the shown Lineweaver-Burk plots would you expect observe when benzylsuccinic acid I used to inhibit Carboxypeptidase A enzymatic activity? (Choose from options N-R) Increasing [1] Benzylsuccinic acid (shown below) has been identified as an inhibitor of carboxypeptidase A. Based on your understanding of enzyme- inhibitor interactions, identify a likely mechanism of inhibition by benzylsuccinic acid. (Choose from options A-E) in-o CH3 1/S) O V.(min) 20 Zn + No inhibitor H₂N Products of peptidase reaction lle Val -1/KM Increasing (1) Arg IV max IASI m=0
Part C: 1/vo A Which of the shown Lineweaver-Burk plots would you expect enzymatic activity? (Choose from options N-R) B Increasing (1) 1/Vmax 1/[S] [1] = 0 A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibitior E. Non-competitive inhibitor F. G. I only H. Il only 1. Ill only J. II and III only K. I and II only L. I, II and III M. N. Graph A O. Graph B P. Graph C Q. Graph D R. None of the given graphs 04/1 -1/KM Increasing [1], (1=0 1/[S] C ( N
Transcribed Image Text:Part C: 1/vo A Which of the shown Lineweaver-Burk plots would you expect enzymatic activity? (Choose from options N-R) B Increasing (1) 1/Vmax 1/[S] [1] = 0 A. Competitive inhibitor B. Irreversible inhibitor C. Allosteric inhibition D. Uncompetitive inhibitior E. Non-competitive inhibitor F. G. I only H. Il only 1. Ill only J. II and III only K. I and II only L. I, II and III M. N. Graph A O. Graph B P. Graph C Q. Graph D R. None of the given graphs 04/1 -1/KM Increasing [1], (1=0 1/[S] C ( N
Expert Solution
steps

Step by step

Solved in 3 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS