Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Based on your understanding of the binding of insulin, select all of the following events that you would expect to occur in muscle cells due to insulin binding to receptors.
Group of answer choices

a. Glycogen synthesis is activated

b. PFK is stabilized in the R-state and glycolysis is activated 

c. GLUT4 (transporters) are increased in concentration at the plasma membrane

d. Fructose 2,6-bisphosphate increased levels aid in stabilization of the T-state fructose 1,6-bisphosphatase 

e. Gluconeogenesis is activated in response to elevated fructose 2,6-bisphosphate levels

f. Phosphorylation cascades allow for covalent modifications that would aid in the breakdown of glycogen to allow for increased levels of glucose 6-phosphate in the cell

g. Hexokinase is inhibited so glucose will not be brought into the cell in high amounts

h. Glycogen breakdown pathway is inactivated

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