Aspartic acid has a side chain bearing a carboxylic acid group; its pKa is 4. The a-amino and a-carboxylic groups have pKa values similar to those of alanine. Determine the net charge on an aspartic acid molecule at the following pH values: (for additional ungraded practice, see if you can identify which of the curves from the previous question correspond to Aspartic acid) pH = 1 pH 2.5 pH=4 +2 +1 0 pH = 9 -1 pH = 13 -2

Introduction to General, Organic and Biochemistry
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Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
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Chapter22: Proteins
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Aspartic acid has a side chain bearing a carboxylic acid group; its pKa is 4. The a-amino and
a-carboxylic groups have pKa values similar to those of alanine. Determine the net charge
on an aspartic acid molecule at the following pH values:
(for additional ungraded practice, see if you can identify which of the curves from the
previous question correspond to Aspartic acid)
pH = 1
pH 2.5
pH=4
+2
+1
0
pH = 9
-1
pH = 13
-2
Transcribed Image Text:Aspartic acid has a side chain bearing a carboxylic acid group; its pKa is 4. The a-amino and a-carboxylic groups have pKa values similar to those of alanine. Determine the net charge on an aspartic acid molecule at the following pH values: (for additional ungraded practice, see if you can identify which of the curves from the previous question correspond to Aspartic acid) pH = 1 pH 2.5 pH=4 +2 +1 0 pH = 9 -1 pH = 13 -2
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