What is thethermodynamic product obtained from the addition of 1 equivalent of HBr to buta-1,3-diene? 2-Bromobut-2-ene 2-Bromobut-1-ene 1-Bromobut-2-ene 3-Bromobut-1-ene

Treatment of the following stereoisomer of 1-bromo-1,2-diphenylpropane with sodium ethoxide in ethanol gives a single stereoisomer of 1,2-diphenylpropene. I H C6H5 H3C Br C6H5 CH3CH2O Na+ CH3CH2OH Draw the E2 elimination product of the reaction. Take into account that the starting stereochemistry affects the resulting double bond stereochemistry. • Consider E/Z stereochemistry of alkenes. • Do not show stereochemistry in other cases. •You do not have to explicitly draw H atoms. • In cases where there is more than one answer, just draw one.

Draw the product that could be formed when 2,3- dimethylbuta-1,3-diene reacts with (E)-2-butenedinitrile. Include any relative stereochemistry. CN NC

Which set of reagents is used for the Markovnikov addition of water to an alkene without rearrangement? A. BH3, THF followed by H₂O2, NaOH B. H₂O, H₂SO4 C. Hg(O₂CCH3)2, H₂O followed by NaBH4, NaOH D. none of these

what product would you expect from the SN1 reaction of (S)-3-methyloctan-3-ol[(S)-3-hydroxy-3-methyloctane] with HBr? Show the stereochemistry of both starting materail and product.

Elimination reactions of cis-and trans-1-bromo-2-methylcyclohexanes with NaOEt in E1OH can give the same or different main product, 1-methylcyclohexene (1) or 3-methylcyclohexene (2). Which of (a)-(d) indicates the main products? Br Br NaOEt NaOEt ELOH ELOH Me `Me Me Me cis 1 2 trans A. 1 both from the cis and trans substrate B. 2 both from the cis and trans substrates C. 1 from the cis and 2 from the trans substrate D. 2 from the cis and 1 from the trans substrate

зн Alc' 9 re -> witiple alkylation 1. Which of the following reactions would be best to perform the following reaction? ОН A) SOCI₂ then potassium tert-butoxide C) CH3 MgBr then H₂O E) KMnO4 (cold) 4. Which of the following is a conjugated diene? ? CHEM 242 Activity 2.1-Conjugated n-Systems B) H₂SO4/H₂O and heat D) PBr3 then lithium diisopropylamide (LDA)

What is the most probable elimination product when 4-chlorocyclohexene is reacted with alcoholic KOH? 1,3-cyclohexadiene 1,4-cyclohexadiene Cyclohexane Cyclohexene

Draw the products of each of the following SN2/E2 reactions. If the products can exist as stereoisomers, show which stereoisomers are formed. a.(3S,4S)-3-bromo-4-methylhexane + CH3O- b. (3R,4R)-3-bromo-4-methylhexane + CH3O- c. (3S,4R)-bromo-4-methylhexane + CH3O- d. (3R,4S)-3-bromo-4-methylhexane + CH3O-

Treatment of the following stereoisomer of 1-bromo-1,2- diphenylpropane with sodium ethoxide in ethanol gives a single stereoisomer of 1,2-diphenylpropene. H3C H C6H5 H C6H5 Br ***I CH3CH₂O Na+ Draw the E2 elimination product of the reaction. Take into account that the starting stereochemistry affects the resulting double bond stereochemistry. CH₂CH₂OH Consider E/Z stereochemistry of alkenes. Do not show stereochemistry in other cases. • You do not have to explicitly draw H atoms. • In cases where there is more than one answer, just draw one. Sn [F ?